Low-Cost Portable Inhalation Therapy Platform for Needle-Free DNA-Based Influenza Vaccination
Low-Cost Portable Inhalation Therapy Platform for Needle-Free DNA-Based Influenza Vaccination
批准号:
nhmrc : GNT1112870
负责人:
A/Pr Aeron Hurt
金额:
$52.46万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Development Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
流感影响到全球很大一部分人口,在大流行时可导致许多人死亡。DNA流感疫苗克服了与常用的基于弱化病毒的疫苗相关的严重副作用的可能性,可以快速生产,并且无需冷藏即可轻松运输。然而,DNA疫苗不稳定,难以交付。我们建议用一种低成本的便携式手持设备来解决这个问题,这种设备可以简单地吸入疫苗。
英文摘要
Influenza affects a large proportion of the global population and can result in many deaths in a pandemic. A DNA influenza vaccine overcomes the possibility of severe side effects associated with commonly used vaccines based on weakened viruses and can be rapidly produced and easily transported without refrigeration. DNA vaccines are however unstable and difficult to deliver. We propose to address this with a low-cost and portable handheld device which allows the vaccine to simply be inhaled.
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