WUSTL Transdisciplinary Pre- and Postdoctoral Training Program in Obesity and Cardiovascular Disease

 描述（由申请人提供）：肥胖和心血管疾病（CVD）的生物，行为，社会和环境风险因素的复杂性需要团队科学，能够跨越学科特定筒仓的边界，从跨学科的方法进行和评估研究，以预防和治疗肥胖和CVD整个生命周期。努力促进受过多个领域和不同级别培训的科学家之间加强合作，不仅有价值，而且对解决此类复杂问题至关重要。因此，我们建议在圣路易斯华盛顿大学（WUSTL）的肥胖和心血管疾病的创新，跨学科的前和博士后培训计划。WUSTL是一个世界级的研究机构，通过其独特的，大学的，跨校园和部门的科学环境，促进跨学科的，转化研究。该方案将：1）招募和培训有才华的跨学科博士前和博士后学员; 2）为学员提供协作，跨学科的导师团队; 3）在未来的科学劳动力的目标多样性;和4）提供肥胖/心血管疾病研究的道德和社会责任行为的培训。肥胖问题国际权威机构Denise Wilfley博士（主任）和Samuel Klein博士（联合主任）将领导该计划，并得到生物医学，认知和行为以及人口健康科学15个部门的高素质，主要和共同导师的支持。初级导师在培养多产科学家方面非常成功;在过去10年中，78%和87%的博士前和博士后学员分别从事研究职业或培训。在研究人员中，67%和72%获得了外部资金。我们的导师资金充足（93%由NIH资助），并有很强的合作关系，以促进4名博士前和4名博士后学员的培训。结合来自不同背景的博士前和博士后学员（例如，遗传学、分子细胞生物学、心理学、社会工作、公共卫生、神经科学）创造了一个独特的动态培训环境。WUSTL营养肥胖研究中心，临床和转化科学研究所，公共卫生研究所，糖尿病心血管疾病中心和糖尿病转化研究中心将提供基础设施和最先进的资源，以支持学员参与变革，转化科学。由学员，计划管理和协作指导团队进行的计划评估将确保学员实现短期和长期的生产力指标，使他们能够成功获得学术职位和独立赠款。多元化咨询委员会将协助招聘和留住来自不同背景的高素质受训人员。我们提出的培训计划不仅在设计上具有创新性，而且在恒星导师的指导下采用团队科学方法，我们的学员将准备创建并为跨学科的科学方法做出贡献，这些方法更有可能为肥胖和CVD的复杂问题提供创新的解决方案，而不是以前由单个科学家在单一学科领域进行的研究。(End摘要）

 DESCRIPTION (provided by applicant): The complexities of biological, behavioral, social, and environmental risk factors for obesity and cardiovascular disease (CVD) necessitate team science, capable of crossing the boundaries of disciplinary-specific silos to conduct and evaluate research from a transdisciplinary approach to prevent and treat obesity and CVD across the lifespan. Efforts to facilitate greater collaboration among scientists trained across many fields and levels of training are not only valuable but essential to solving such complex problems. Thus, we propose an innovative, transdisciplinary pre- and postdoctoral training program in obesity and CVD at Washington University in St. Louis (WUSTL). WUSTL is a world-class research institution promoting transdisciplinary, translational research through its unique, collegial, scientific environment across campuses and departments. This program will: 1) recruit and train talented transdisciplinary pre- and postdoctoral trainees; 2) provide trainees with collaborative, transdisciplinary mentorship teams; 3) target diversity in the future scientific workforce; and 4) provide training in the ethical and socially responsible conduct of obesity/CVD research. International authorities on obesity, Denise Wilfley, PhD (Director) and Samuel Klein, MD (Co-Director), will lead the program, supported by highly- qualified, primary and co-mentors spanning 15 departments in the biomedical, cognitive and behavioral, and population health sciences. Primary mentors have been extremely successful in training productive scientists; over the last 10 years, 78% and 87% of past pre- and postdoctoral trainees, respectively, are in research careers or training. Of those in research, 67% and 72% have obtained external funding. Our mentors are well funded (93% with NIH funding) and have strong collaborative ties to facilitate the training of 4 pre- and 4 postdoctoral trainees. Combining pre- and postdoctoral trainees from diverse backgrounds (e.g., genetics, molecular cell biology, psychology, social work, public heath, neurosciences) creates a uniquely dynamic training environment. The WUSTL Nutrition Obesity Research Center, Institute of Clinical and Translational Sciences, Institute for Public Health, Diabetic Cardiovascular Disease Center, and Center for Diabetes Translation Research will provide infrastructure and state-of-the-art resources to support trainees' engagement in transformative, translational science. Program evaluations conducted by trainees, program administration and collaborative mentorship teams will ensure trainees achieve short- and long-term indicators of productivity positioning them for success in obtaining academic positions and independent grants. The Diversity Advisory Committee will assist in the recruitment and retention of highly qualified trainees from diverse backgrounds. Not only is our proposed training program innovative in its design, but using a team science approach guided by stellar mentors, our trainees will be prepared to create and contribute to transdisciplinary scientific approaches that are more likely to yield innovative solutions to the complex problems of obesity and CVD than research previously conducted by individual scientists within a single disciplinary field. (End of Abstract)