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中文摘要
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数据管理和生物统计核心(数据核心)对所有数据进行管理和分析 六个同事核心(行政、临床、神经病理学、神经成像、心理社会、教育),以及 隶属于ADC的个人研究人员。数据核心维护纽约大学ADC收集的所有数据 一个中央数据库,将数据传输到国家阿尔茨海默氏症协调中心(NACC),以创建 全国所有ADC的通用数据库,并提供咨询和实践帮助 对纽约大学ADC的所有合作研究人员进行实验设计和统计分析。The Rapid 老龄化和痴呆症相关数据的大小、类型和复杂性的增加要求数据 CORE扩展其功能,以(1)促进通过互联网进行信息交流,以及(2)引入、 应用和开发新的统计方法,进行全面的数据分析。数据核心的具体目标是: 1.继续提供我们传统的数据管理和统计咨询服务,包括 管理和更新中央数据库,提供试验设计和咨询服务 统计分析,并在执行和利用方面与国家反腐败委员会保持密切合作 所有ADC的统一数据集(UDS)。 2.进一步开发和维护一个安全的网上数据库,符合机构标准 由纽约大学设置,用于中心内和中心之间的多用户在线信息交换,NACC和 其他合作者。我们正在将我们的Visual FoxPro数据库服务器升级到现代的基于Web的运行状况 护理管理软件(临床数据库+临床管理)-Velos,由纽约大学赞助。 3.积极发起、发展、参与和指导我们内部和同事之间的统计分析 核心/中心。数据核心分析师(包括实习生)被分配到其他核心以增加 相互交流和理解,并在设计与ADC相关的研究方面促进密切合作 以及对ADC数据的分析。数据核心领导者与核心分析师和ADC举行两周一次的会议 对协作分析感兴趣的研究人员。我们还积极参与研究论文的撰写。 4.对中心附属研究人员进行数据库利用和相关统计分析方法的培训。 这一点已经并将继续通过一个全面的互联网站来实现,该网站包含详细的 教育专题和在线帮助,以及每月统计研讨会。 5.积极参与和牵头拨款申请,以进一步提高数据核心资金水平。
英文摘要
The Data Management and Biostatistics Core (Data Core) performs data management and analysis for all six fellow cores (Administrative, Clinical, Neuropathology, Neuroimaging, Psychosocial, Education), and for individual researchers affiliated with the ADC. The Data Core maintains all data collected by the NYU ADC in a centralized database, transfers data to the National Alzheimer's Coordinating Center (NACC) to create a common database for all ADC's across the country, and offers consultation and hands-on help in experimental design and statistical analysis to all collaborating investigators in the NYU ADC. The rapid increase in the size, the type and the complexity of aging and dementia related data demands that the Data Core expand its functions in order to (1) facilitate information exchange via the Internet, and (2) introduce, apply and develop novel statistical methods for comprehensive data analysis. Data Core Specific Aims are: 1. Continue to provide our traditional data management and statistical consultation services which include managing and updating the centralized Center database, offering consultation on experimental design and statistical analysis, and maintaining close collaboration with the NACC in the implementation and utilization of the uniform data set (UDS) for all ADC's. 2. Further develop and maintain a secure Web-based database, conforming to the institutional standards set by NYU, for multi-user on-line information exchange within the Center and between Centers, NACC and other collaborators. We are upgrading our Visual FoxPro database server to a modern web-based health care management software (clinical database plus clinical management) — Velos, sponsored by NYU. 3. Actively initiate, develop, participate in and direct statistical analyses within and between our fellow cores/centers. Data Core analysts (including student trainees) are assigned to fellow cores to increase mutual interactions and understanding, and foster close collaborations in the design of ADC related studies and the analysis of ADC data. Data Core leader conducts biweekly meetings with Core analysts and ADC researchers interested in collaborative analysis. We also actively participate in research paper writing. 4. Educate Center affiliated researchers on database utilization and related statistical analysis methods. This has been and will continuously be achieved through a comprehensive internet site with detailed education topics and on-line help as well as monthly statistics seminar. 5. Actively participate in as well as lead grant applications to further increase Data Core funding levels.
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Data Management and Statistical Core
Data Management and Statistical Core
Biostatistics/Bioinformatics Core
Biostatistics/Bioinformatics Core