2019 Cell Growth and Proliferation Gordon Research Conference and Gordon Research Seminar

总结 这份提案是向NIH请求对戈登研究会议的部分支持 (GRC)“细胞生长和增殖：正常和异常的细胞周期变化。会议将聚集 150-200名研究生，博士后研究员，工作人员科学家，初级和高级教师，实验室领导人在 工业界和政府讨论他们最近未发表的发现。会议将 关注正常细胞增殖控制的机制，正常细胞增殖所需的许多细胞周期变化， 生长以及癌症和其它增殖性疾病中的各种异常细胞周期扰动。的 节目的形式是邀请的演讲者与从摘要中选择的演讲者的大致相等的混合 2019年春季提交，强调来自多个国家的发言者的广泛代表性 学科，职业阶段，人口和地理背景。主席和副主席是 特别致力于创建一个多样化和包容性的会议，反映细胞周期的广度 控制和基础癌细胞生物学研究，展示了初级和 该领域的资深成员。计划的正式研究会议的主题包括一个开幕会议， 癌症细胞生物学和其他会议，包括1）基因组结构和基因组不稳定性，2） 定量细胞周期动力学，3）染色体分离和胞质分裂，4）细胞间异质性，5） 磷酸化和泛素化，6）癌症和靶向治疗，7）代谢和信号传导，8） 分化和细胞周期重塑。此外，将有四个海报会议和大量的非结构化 非正式网络时间我们还将利用资金部分支持附属的戈登研究所 研讨会，一个为期1.5天的活动，紧接在GRC之前，由博士后和学生组织。 本次活动将于2019年7月7日至12日在佛蒙特州西多佛的Mount Snow Resort举行，是唯一一次大型 计划于2019年在北美举行的细胞周期调节领域会议。它的独特之处在于 广泛，因为它汇集了来自学术和生物学领域的基础和转化生物学研究人员， 行业设置。

SUMMARY This proposal is a request for support from the NIH for partial support of the Gordon Research Conference (GRC) “Cell Growth and Proliferation: Normal and Abnormal Cell Cycle Variations.” The conference will gather 150-200 graduate students, postdoctoral fellows, staff scientists, junior and senior faculty, lab leaders in industry and government for discussions of their most recent unpublished discoveries. The Conference will focus on mechanisms of normal cell proliferation control, the many cell cycle variations required for normal growth, and the variety of abnormal cell cycle perturbations in cancer and other proliferative diseases. The program format is an approximately equal mix of invited speakers with speakers selected from abstract submitted in the spring of 2019 with an emphasis on broad representation of speakers from multiple disciplines, career stages, demographic and geographic backgrounds. The Chair and Vice Chair are specifically committed to creating a diverse and inclusive conference that reflects the breadth of cell cycle control and fundamental cancer cell biology research and that showcases the contributions of both junior and senior members of the field. Topics of formal research sessions planned include an opening session focused on Cancer Cell Biology and additional sessions including 1) genome architecture and genome instability, 2) quantitative cell cycle dynamics, 3) chromosome segregation and cytokinesis, 4) intercellular heterogeneity, 5) phosphorylation and ubiquitination, 6) cancer and targeted therapies, 7) metabolism and signaling, 8) differentiation and cell cycle remodeling. In addition, there will be four poster sessions and ample unstructured time for informal networking. We will also use funding to partially support the affiliated Gordon Research Seminar, a 1.5 day event that immediately precedes the GRC organized by and for postdocs and students. This event will be held at Mount Snow Resort, West Dover, Vermont from July 7-12, 2019 and is the only major conference for the cell cycle regulation field in North America planned for 2019. It is relatively unique in its breadth because it brings together researchers focused on basic and translational biology from academic and industry settings.