Multidisciplinary Investigations in Visual Science

项目摘要 这个NEI中心核心应用程序的目标是加强NEI资助的研究活动 爱荷华州大学的研究人员。这将通过提供补充服务来实现 丹每个核心将提供一系列服务-由熟练的技术人员执行，并由 经验丰富的NEI资助的教师，采用标准化的，自动化的程序时， 可能集中化（允许专业化和随之而来的 效率）和各种核心模块提供的服务的广度， 为爱荷华州大学的所有视觉研究人员提供实用工具并提高生产力。 这支持了三个主要焦点：1）组织学和超微结构研究，2）详细的表型， 小鼠，以及3）大规模图像和基因型数据的计算分析。这些能力 所有这些都需要专门的设备和训练有素的工作人员， 实验室采用这些技术。

PROJECT SUMMARY The goal of this NEI Center Core application is to enhance the research activities of NEI-funded investigators at The University of Iowa. This will be achieved by providing a complement of Service Cores. Each Core will offer a set of services - performed by skilled technical staff and supervised by experienced NEI-funded faculty members, employing standardized, automated procedures when possible. The combination of centralization (allowing specialization and concomitant increases in efficiency) and the breadth of services available from the various Core Modules are expected to provide utility and increased productivity to all vision researchers at The University of Iowa. This supports three primary foci: 1) histological and ultrastructural studies, 2) detailed phenotyping in the mouse, and 3) computational analysis of large-scale image and genotype data. These capabilities all require specialized equipment and highly trained staff that would be inefficient to duplicate in every lab employing these techniques.