13th International Conference on Cerebral Vascular Biology

摘要 第十三届国际脑血管生物学大会(CVB 2019；www.CVB2019.com)将 将于2019年6月25日至28日在佛罗里达州迈阿密的万豪迈阿密比斯坎湾酒店举行。CVB 会议是一年两次的会议，为来自世界各地的科学家提供一个讨论的论坛。 他们在脑血管生物学方面的前沿研究，重点是中枢神经系统屏障，主要是血液- 脑屏障(BBB)。CVB 2019迈阿密将是一个非常成功的系列会议的延续， 是1992年在明尼苏达大学德卢斯分校发起的。为了强调重要性和 CVB系列的国际焦点，会议在北美、欧洲和 亚洲/澳大利亚。CVB 2019在缺席16年后重返美国，成为首屈一指的最佳- 成立脑血管生物学国际会议。CVB 2019将吸引科学家 来自广泛的背景和学科，他们对脑血管有共同的兴趣 生物学。通过将基础、翻译和临床领域的不同背景的科学家聚集在一起 通过研究，会议将促进脑血管话题中共同主题的出现。 这将为成功的脑部疾病的治疗干预构建战略 强脑血管成分和/或突出表现为血脑屏障功能障碍。整体而言 CVB 2019的目标是成为最新科学技术信息交流的催化剂 与血脑屏障生物工程相关的发现，高效的药物输送到大脑，以及 血脑屏障参与大脑的生理和病理，包括神经感染， 神经退行性疾病和成瘾研究。与这一目标相一致，参与者将 讨论当前和未来围绕脑血管生物学的研究，如生物学和结构 神经血管单位和细胞连接蛋白，构建和模拟血脑屏障，递送 跨越血脑屏障的各种药物，中枢神经系统屏障在神经疾病病理中的作用， 以及通过瞄准大脑屏障来逆转这些疾病的治疗策略。重点将是 放在涉及大脑疾病的综合科学、翻译方面和临床研究上 可应用于治疗的血管系统。会议期间讨论的其他新议题将 涉及生活方式对脑屏障调节的影响，脑老化的脑血管病理， 针对再生医学的脑血管系统，以及肠道-脑轴的作用。几个 活动将专门针对受训人员、早期调查人员以及包括来自 代表不足的群体。会议大力促进各民族之间的种族和性别多样性 将为演讲者和与会者以及有特殊需要的与会者提供住宿。

ABSTRACT The 13th International Conference on Cerebral Vascular Biology (CVB 2019; www.CVB2019.com) will be held at the Marriott Miami Biscayne Bay hotel from June 25-28, 2019 in Miami, FL. The CVB conferences are bi-annual meetings that provide a forum for scientists from around the world to discuss their cutting edge research on cerebral vascular biology with a focus on CNS barriers, primarily the blood- brain barrier (BBB). CVB 2019 in Miami will be a continuation of a very successful conference series that was initiated in 1992 at the University of Minnesota at Duluth. To emphasize the importance and international focus of the CVB series, the conferences rotate between North America, Europe, and Asia/Australia. CVB 2019 is returning to the US after 16 years of absence as the premier and best- established international conference related to cerebral vascular biology. CVB 2019 will attract scientists from a broad range of backgrounds and disciplines who share a common interest in cerebral vascular biology. By bringing together scientists from diverse backgrounds in basic, translational, and clinical research, the meeting will promote the emergence of common themes across cerebrovascular topics. This will structure strategies for successful therapeutic interventions in the brain diseases that have strong cerebrovascular components and/or are underlined by the dysfunction of the BBB. The overall goal of CVB 2019 is to serve as a catalyst for exchange of information on the latest scientific discoveries related to the bioengineering of the BBB, efficient drug delivery into the brain, and involvement of the BBB in the physiology and pathology of the brain, including neuroinfections, neurodegenerative diseases, and addiction research. Consistent with this goal, the participants will discuss current and future research surrounding cerebral vascular biology, such as biology and structure of the neurovascular unit and cell junction proteins, constructing and modeling the BBB, delivery of various types of drugs across the BBB, the role of CNS barriers in the pathology of neurological diseases, and therapeutic strategies to reverse these diseases by targeting the brain barriers. Emphasis will be placed on integrative science, translational aspects, and clinical research on disorders involving cerebral vasculature that can be applied to therapy. Other emerging topics discussed during the conference will involve impact of life style on modulation of brain barriers, cerebrovascular pathology of the aging brain, targeting cerebral vasculature for regenerative medicine, and the role of the gut-brain axis. Several activities will be dedicated to Trainees, Early Stage Investigators, and the inclusion of researchers from underrepresented groups. The conference strongly promotes ethnic and gender diversity among the speakers and participants, and accommodations for attendees with special needs will be provided.