NEI Center Core Grant for Vision Research

摘要 总括 愿景研究核心资助金的总体目的是为 提高并加速加州大学视觉研究界的工作效率和影响力 加利福尼亚州，圣地亚哥。具体地说，愿景研究核心赠款将利用尚未完成的基本 国家眼科研究所的科学和临床研究专长通过提供重要的 将资源和服务组织成以下4个不同的核心。 1.生物统计核心将为视觉研究界提供专门的统计专门知识，网址为 加州大学圣迭戈分校。有几个常见的分析主题和统计问题可以有效地解决 并让熟悉眼科研究的专门生物统计师分析与视力相关的数据，从而提高效率 并确保结果的严谨性和透明度。 2.动物结构和功能核心将提供共享仪器和一名技术人员协助 与动物的眼结构成像和功能成像相结合。 3.计算眼科核心提供i)专用高性能CPU和GPU 计算资源二)计算机程序员，三)机构软件许可证和四)安全文件 共享和备份服务，以支持加州大学圣迭戈分校的细胞、动物和人类视力研究。 4.组织处理和组织学核心提供关于以下方面的眼组织的快速表征 组织学、免疫组织化学和共聚焦显微镜，由辅助仪器和技术人员提供 熟悉眼部解剖学和适当处理眼组织所需的技术。 这些核心将提高加州大学圣迭戈分校视觉科学家的效率和生产力，并通过提供 个人调查员无法获得的核心服务。核心赠款基础设施和资源 还利用每个参与调查人员的专业知识来加强多学科合作 整个加州大学圣地亚哥分校视力研究社区的利益。

SUMMARY Overall The overall purpose of the Vision Research Core Grant is to provide core services and resources to enhance and accelerate the productivity and impact of the vision research community at University of California, San Diego. Specifically, the Vision Research Core grant will leverage the outstanding basic science and clinical research expertise of National Eye Institute funded investigators by providing important resources and services organized into the following 4 distinct cores. 1. The Biostatistics Core will provide dedicated statistical expertise for the vision research community at UCSD. There are several common analysis themes and statistical issues that can be addressed effectively and efficiently by having a dedicated biostatistician familiar with eye research to analyze vision related data and to ensure rigor and transparency of the results. 2. The Animal Structure and Function Core will provide shared instrumentation and a technician to assist with ocular structural imaging and functional imaging in animals. 3. The Computational Ophthalmology core provides i) dedicated high-performance CPU and GPU computing resources ii) a computer programmer, iii) institutional software licenses and iv) secure file sharing and backup services to support UCSD's cellular, animal and human vision research studies. 4. The Tissue Processing and Histology Core provides rapid characterization of eye tissue with respect to histology, immunohistochemistry and confocal microscopy by supporting instrumentation and a technician who is familiar with ocular anatomy and techniques required to properly process ocular tissues. These cores will improve the efficiency and productivity and impact of UCSD vision scientists by providing core services that are unavailable to individual investigators. The core grant infrastructure and resources also leverages the expertise of each participating investigator to enhance multidisciplinary collaboration for the benefit of the entire UCSD vision research community.