An Integrative Science Approach to Resilience: The Notre Dame Study of Health & Well-being

项目摘要 这项建议旨在研究生活压力对健康的影响。 成年人一生中的认知、身体和心理健康，以及可能 保护个人免受暴露在逆境中的不良影响。我们计划收集面对面的认知和 参加圣母大学健康与福祉研究的#名个人的健康数据。 至少有7年的纵向问卷数据和4次56天的每日日记数据。一秒钟 目的是增加一个基于实验室的实验应力操纵来试验a)最优的方法 实验操纵压力，b)评估随后对生理系统的干扰 受压力影响(如皮质醇、α-淀粉酶、心率、面部表情)，以及c)应对评估 区分应激反应调节的资源。我们将充分利用其独特的科学价值 NDHWB的一项广泛议程是对成年后的风险和韧性进行研究。

Project Summary This proposal is designed to investigate the myriad pathways through which life stress contributes to the cognitive, physical and mental health across the adult lifespan, and of the resilience mechanisms that may protect individuals from the ill-effects of exposure to adversity. We plan to collect in-person cognitive and health data from ## individuals participating in the Notre Dame Study of Health & Well-Being (NDHWB) who have at least 7 years of longitudinal questionnaire data and 4 bursts of 56-day daily diary data. A second objective is to add a laboratory-based experimental stress manipulation to pilot a) optimal methods to experimentally manipulate stress, b) the assessment of subsequent disruption to physiological systems affected by stress (e.g., cortisol, alpha amylase, heart rate, facial expressions), and c) the appraisal of coping resources that differentiate the regulation of stress response. We will capitalize on the unique scientific value of the NDHWB to pursue a broad agenda of research on risk and resilience across adulthood.