Maintenance and Incidence of ME/CFS following Mono

摘要 新冠肺炎发病的行为和病理生理基础还知之甚少。 从2014年到2018年，我们的研究组收集了4501名年轻人的心理和生物数据 成年人。我们目前得到资助，就ME/CFS的症状重新联系和采访这些受试者。 这项补充资金申请将使我们能够收集与COVIDF-19感染有关的数据，并 从感染中恢复与不恢复的对比也是如此。使用我们的基线数据，我们将能够比较 疫情前和疫情期间年轻人的生物和行为数据，我们将能够 比较那些患上新冠肺炎的人和那些没有患上新冠肺炎的人，以确定可能的诱因 并确定那些完全康复的人与那些没有完全康复的人。我们强调紧急情况 请求的性质，因为我们将需要从6月、7月和8月开始看这些患者。这群人是 在我们努力识别导致患者患新冠肺炎的风险因素方面具有重要意义，这可能有助于 揭示新冠肺炎的内在机制。我们相信我们的建议解决了对 严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的生物学效应和 新冠肺炎对神经系统的影响“。

Abstract Behavioral and pathophysiological underpinnings of the development of COVID-19 are poorly understood. From 2014 through 2018, our research group collected psychological and biological data of 4,501 young adults. We are currently funded to re-contact and interview these subjects regarding symptoms of ME/CFS. This supplemental funding request would allow us to also collect data involving COVIDF-19 infection and recovery vs nonrecovery from that infection as well. Using our baseline data, we will be able to compare the biological and behavioral data of young adults prior to the epidemic and during the epidemic, we will be able to compare those who became ill with COVID-19 and those who did not, to identify possible predisposing characteristics and to determine those who fully recovered vs those who did not. We emphasize the urgent nature of the request, as we will need to see these patients starting in June, July, and August. This cohort is significant in our effort to identify risk factors predisposing patients to developing COVID-19, which may help uncover underlying mechanisms of COVID-19. We believe our proposal addresses an urgent need for research on “biological effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and effects of COVID-19 on the nervous system”.