Reducing Weight Stigma to Improve Long-Term Weight Loss

项目摘要/摘要 我的长期职业目标是成为一名独立调查员，拥有一个多学科的项目 肥胖症的治疗研究。作为一名临床心理学家，我之前的培训重点是识别和 减少肥胖的有害心理社会后果，包括基于体重的污名。然而，为了 实现我的目标，即进行研究，以减少对健康的不利影响，并提高 对于肥胖者来说，我必须在肥胖症的临床治疗方面进行额外的培训。K23 获奖将使我能够将90%的精力用于填补我培训中的关键空白，并进行 有助于我成为肥胖症的独立临床研究员的研究。 拟议的培训计划将通过解决三个基本方面来支持我的职业目标：1) 进行肥胖治疗的临床试验；2)评估和促进研究参与者对 体力活动；3)了解增加心脏代谢性疾病风险的生物机制。我 将通过以下方式获得这些领域的培训：接受该领域专家导师的指导；完成 课业和参加研讨会；从事相关的研究活动。这个训练计划将给我带来 在K23奖励期结束前准备一份成功的R01申请所需的知识和技能。 我的研究项目将补充我的培训目标，同时也建立在我之前的耻辱基础上- 相关的研究工作。在一项随机对照试验中，我将测试一种长期减肥的效果 新的临床干预措施，旨在帮助肥胖患者应对体重污名，与。 标准行为减肥。我相信，减少WBI会通过增加 体力活动，这是一种长期减肥效果更好的行为。这项研究项目 还将纳入心脏代谢风险的评估，以确定减少WBI是否有助于改善 身体健康。这项拟议的研究项目可能会对增强 治疗肥胖，减少体重污名的负面影响。 宾夕法尼亚大学体重和饮食失调中心的环境 (宾夕法尼亚州立大学)非常适合支持我的培训和研究需求。该中心将为以下方面提供实用资源 数据管理和参与者招募、评估和治疗。我将主要接受指导 来自该中心主任托马斯·瓦登博士。额外的指导和研究资源将是 由John Jakicic博士(该大学身体活动和体重管理中心主任)提供 和丹尼尔·雷德博士(宾夕法尼亚大学心血管预防中心主任 计划)。除了这些特定的中心，我还将有机会进入宾夕法尼亚大学的其他几个学术项目 支持我的培训需求，包括糖尿病、新陈代谢和肥胖研究所。宾夕法尼亚大学提供了 非常丰富的环境，将使我能够实现我的研究和培训目标。

PROJECT SUMMARY/ABSTRACT My long-term career goal is to be an independent investigator with a multidisciplinary program of research in the treatment of obesity. As a clinical psychologist, my prior training has focused on identifying and reducing harmful psychosocial consequences of obesity, including weight-based stigma. However, in order to achieve my goal of conducting research to reduce adverse health consequences and improve quality of life for persons with obesity, it is essential that I have additional training in the clinical treatment of obesity. The K23 award would enable me to devote 90% of my effort to filling critical gaps in my training and to conducting research that will facilitate my becoming an independent clinical investigator in obesity. The proposed training plan will support my career goals by addressing three fundamental areas: 1) conducting clinical trials in obesity treatment; 2) assessing and promoting study participants' engagement in physical activity; and 3) understanding biological mechanisms that increase risk for cardiometabolic disease. I will obtain training in these areas by: receiving guidance from expert mentors in the field; completing coursework and attending seminars; and engaging in related research activities. This training plan will give me the knowledge and skills needed to prepare a successful R01 application by the end of the K23 award period. My research project will complement my training objectives while also building upon my prior stigma- related research efforts. In a randomized controlled trial, I will test the effects on long-term weight loss of a novel clinical intervention designed to help individuals with obesity cope with weight stigma, combined with . standard behavioral weight loss. I believe that reducing WBI will improve long-term weight loss by increasing physical activity, a behavior consistently associated with greater long-term weight loss. This research project will also incorporate assessments of cardiometabolic risk to determine whether reducing WBI helps to improve physical health. The proposed research project could have significant clinical implications for enhancing the treatment of obesity and reducing the negative effects of weight stigma. The environment at the Center for Weight and Eating Disorders at the University of Pennsylvania (Penn) is ideal for supporting my training and research needs. The Center will provide practical resources for data management and participant recruitment, assessment, and treatment. I will receive mentorship primarily from Dr. Thomas Wadden, the Center's director. Additional mentorship and research resources will be provided by Dr. John Jakicic (director of the Physical Activity and Weight Management Center at the University of Pittsburgh School of Education) and Dr. Daniel Rader (director of the Penn Preventive Cardiovascular Program). Outside of these specific centers, I will have access to several other academic programs at Penn to support my training needs, including the Institute for Diabetes, Metabolism, and Obesity. Penn provides a remarkably rich environment that will enable me to achieve my research and training goals.