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中文摘要
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摘要-管理核心: 该方案项目包括三个科学项目和两个科学核心,汇集了 具有不同背景、动机和专业知识的人员。我们的目标是迅速发现发展中的 急、慢性组织驻留记忆CD8+T细胞的途径和转录程序 感染。我们确定了以下两个成功实现多团队合作的关键挑战:(1) 在所有团队成员中建立和维护共同的愿景,以及(2)建立顺畅和高效 共享数据、试剂和技术,以最好地协调项目之间的实验策略。这个 管理核心将通过以下方式满足这些需求并为计划项目的目标做出贡献:(1) 作为各级和所有有关人员的通信枢纽,同时(2)提供一般行政管理 支持和财政监督。因此,行政核心在方案项目的努力中起着核心作用, 在下文中,我们将介绍其活动的具体情况。 好了!
英文摘要
SUMMARY-ADMINISTRATIVE CORE: This Program Project encompasses three Scientific Projects and two Scientific Cores, bringing together personnel with diverse backgrounds, motivations, and expertise. We aim to rapidly uncover the developmental pathway and transcriptional programming of tissue-resident memory CD8+ T cells in acute and chronic infection. We have identified the following two critical challenges for success of this multi-team effort: (1) building and maintaining a common vision among all team members, and (2) establishing smooth and efficient sharing of data, reagents, and technology, to best coordinate experimental strategy between Projects. The Administrative Core will address these needs and contribute to the goals of the Program Project by (1) acting as a communication hub at all levels and for all involved personnel, while (2) providing general administrative support and fiscal oversight. The Administrative Core thus plays a central role in the Program Project's efforts, and in the following, we lay out the specifics of its activities. !
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Ubiquitin ligase regulation of tissue-resident T cell and anti-tumor activity
Regulation of memory T cell differentiation and long-term maintenance
  • 批准号:
    10683278
  • 项目类别:
  • 资助金额:
    $55.53万
  • 财政年份:
    2020
  • 负责人:
    Ananda W Goldrath
  • 依托单位:
Regulation of memory T cell differentiation and long-term maintenance
  • 批准号:
    10591871
  • 项目类别:
  • 资助金额:
    $12.34万
  • 财政年份:
    2020
  • 负责人:
    Ananda W Goldrath
  • 依托单位:
Regulation of memory T cell differentiation and long-term maintenance
  • 批准号:
    10024589
  • 项目类别:
  • 资助金额:
    $50.91万
  • 财政年份:
    2020
  • 负责人:
    Ananda W Goldrath
  • 依托单位:
海外基金