Leadership and Administrative Core (LAC)

项目总结/摘要 领导和行政核心的目标是提供，不仅是行政 该中心的监督，但也推进研究老年姑息治疗（GPC）及其 通过一个由相关活动组成的框架进行翻译， 培训人员，支持他们的研究发展，并以努力传播工作结束 改善老年人及其家庭的生活。核心具体目标是促进和 支持GPC的科学创新，传播可用于临床转化的研究成果; 协助和监督研究教育部分以及试验和探索性研究 确定、选择和监测初级研究者和试点研究的核心; 协助、监督和协调3个资源核心，确定方法论主题， 推进全球气候变化研究;整合全球气候变化研究中的活动，促进全球气候变化研究中的交流， OAIC核心和调查员;协调OAIC的工作与其他组织的研究活动 方案和机构;并提供行政和通信支持， 协调人类受试者审查，以及核心和项目的财务管理 参与了这次行动在更新中，我们扩大了OAIC的规模，广度和多样性， 我们将继续并扩大OAIC现有的成功努力。的新手 在这次更新中，我们建议1）创建一个新的资源核心， 数据来源，以支持研究，这将促进我们对纵向过程的理解 严重疾病对老年人及其照顾者的影响; 2）在主题上扩大研究， 严重疾病和痴呆症的交叉点;以及将跨越 MS-OAIC核心;围绕两个新主题（痴呆症和严重疾病的交叉点; 和实施科学），将涉及所有核心; 3）创建一个新的胡椒姑息治疗 研究网络;以及4）开展合作努力，以改善 监测涉及严重疾病受试者的临床研究中的严重不良事件。通过 战略性地利用其他计划的资源，这一核心最大限度地发挥了 适度的投资，以创建一个范围全面、在当地具有重要意义的OAIC 影响，与其他OAIC和NIA计划合作，并在其范围内进行国家。

Project Summary/Abstract The goal of the Leadership and Administrative Core is to provide, not only administrative oversight of the Center, but to also advance research in geriatric palliative care (GPC) and its translation through a framework of connected activities that starts with creating a pipeline of trainees, supporting their research development, and ends with efforts to disseminate the work to improve the lives of older persons and their families. The core specific aims are to foster and support scientific innovation in GPC and to disseminate research ready for clinical translation; to assist and oversee the Research Education Component and the Pilot and Exploratory Studies Core in identifying, selecting, and monitoring junior investigators and pilot studies; to assist, oversee, and coordinate 3 resource cores in identifying methodologic themes that will advance research in GPC; to integrate activities and facilitate interchange in GPC among the OAIC cores and investigators; to coordinate the OAIC's work with research activities of other programs and institutions; and to provide administrative and communications support, coordination of human subjects review, and fiscal management for the cores and projects involved in this OAIC. In the renewal, we expand the size, breadth, and diversity of the OAIC's leadership team, and we continue and expand existing successful efforts of the OAIC. New to this renewal, we propose 1) to create a new Resource Core that will leverage a range of existing data sources to support research that will advance our understanding of the longitudinal course of serious illness on older adults and their caregivers; 2) to thematically expand research in the intersection of serious illness and dementia; and implementation science that will cut across the MS-OAIC cores; around two new themes (the intersection of dementia and serious illness; and implementation science) that will involve all cores; 3) to create a new Pepper Palliative Care research network; and 4) to undertake a collaborative effort to improve the process of monitoring serious adverse events in clinical studies involving subjects with serious illness. By strategically leveraging resources from other programs, this core maximizes the impact of a modest investment to create an OAIC that is comprehensive in scope, significant in local impact, collaborative with other OAICs and NIA programs, and national in its reach.