Operational Research for Disease Surveillance Enhancement in Uganda (ORDiSE-U)

项目摘要 随着2002年SARS疫情的爆发和最近西非的埃博拉疫情，威胁 新出现和再次出现的感染是全球面临的真实和现实的危险 社区。乌干达位于这些感染的热点地区。我们建议利用 传染病研究所(IDI)的研究和能力建设经验 及其与乌干达政府的合作和富有成效的关系 开发一种基于证据的疾病监测方法，并 有可能提高国家预防、发现和有效应对 新出现的传染病威胁。IDI是一家研究、临床和培训中心 卓越的基础上，乌干达最著名的学习机构-Makerere 大学。IDI成立于2002年，在以下方面建立了良好的记录 开展与当地相关的研究，以改进护理和变革模式 在艾滋病毒和相关感染领域的政策和实践方面。此外，外展活动 主要由疾控中心和12个PEPFAR作为主要实施伙伴提供资金的方案 采取强有力的卫生系统体制加强办法，以提供预防 为10万多名患者提供护理和治疗。该提案旨在解决 乌干达在疾病监测方面的具体高优先执行差距 评估当前的方法；设计候选模型并严格测试其 在加强监视方面的影响。 它是创新的，因为它利用了实施的持续监视方法 在应急指挥中心(EOC)和公安部的领导下 卫生部；开发和严格评估创新的监测模式。 此外，由乌干达卫生部共同赞助的拟议研究将 可能导致政策和做法的变化，以及加强乌干达的 卫生部开展未来业务研究/实施科学的能力 学习。

Project Abstract With the SARS outbreak in 2002 and more recently with Ebola in West Africa, the threat of emerging and re-emerging infections is a real and present danger facing the global community. Uganda is located in a hot spot for these infections. We propose to leverage the research and capacity building experience of the Infectious Diseases Institute (IDI) and its collaborative and productive relationship with the government of Uganda (GOU) to develop a generate evidence-based approaches to diseases surveillance and potentially enhance the country capacity to prevent, detect and effectively respond to emerging infectious disease threats. The IDI is a research, clinical and training center of excellence based that the pre-eminent institution of learning in Uganda-Makerere University. Established in 2002, the IDI has established a strong track record in performing locally relevant research that leads to improved models of care and changes in policy and practice in the area of HIV and related infections. In addition, the outreach programs largely funded by the CDC and 12 PEPFAR as the key implementing partner took a strong health systems institutional strengthening approach to provide prevention care and treatment to more than 100,000 patients. The proposal seeks to address specific high-priority implementation gaps in diseases surveillance in Uganda by evaluating current approaches; designing candidate model and to rigorously test their impact in enhancing surveillance. It is innovative because it leverages on-going surveillance approaches implemented under the leadership of the emergency operation centre (EOC) and the ministry of Health (MOH); to develop and rigorously evaluate innovative surveillance models. Additionally, the proposed research which is co-sponsored by the Uganda MOH will potentially lead to changes in policy and practice, as well as enhance the Ugandan MOH’s capacity to undertake future operational research/implementation science studies.