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中文摘要
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摘要-行政核心: 该计划项目包括三个科学项目和两个科学核心, 具有不同背景、动机和专业知识的人员。我们的目标是迅速发现发展中的 急性和慢性炎症中组织驻留记忆CD 8 + T细胞的通路和转录编程 感染我们已经确定了这一多团队努力取得成功的两个关键挑战:(1) 在所有团队成员中建立和维护共同愿景,以及(2)建立平稳高效的 共享数据、试剂和技术,以最好地协调项目之间的实验策略。的 行政核心将满足这些需求,并通过以下方式为计划项目的目标做出贡献:(1)采取行动 作为各级和所有相关人员的通信枢纽,同时(2)提供一般行政管理服务, 支持和财政监督。因此,行政核心在方案项目的努力中发挥着核心作用, 下面我们就来具体介绍一下它的活动。 !
英文摘要
SUMMARY-ADMINISTRATIVE CORE: This Program Project encompasses three Scientific Projects and two Scientific Cores, bringing together personnel with diverse backgrounds, motivations, and expertise. We aim to rapidly uncover the developmental pathway and transcriptional programming of tissue-resident memory CD8+ T cells in acute and chronic infection. We have identified the following two critical challenges for success of this multi-team effort: (1) building and maintaining a common vision among all team members, and (2) establishing smooth and efficient sharing of data, reagents, and technology, to best coordinate experimental strategy between Projects. The Administrative Core will address these needs and contribute to the goals of the Program Project by (1) acting as a communication hub at all levels and for all involved personnel, while (2) providing general administrative support and fiscal oversight. The Administrative Core thus plays a central role in the Program Project's efforts, and in the following, we lay out the specifics of its activities. !
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Ubiquitin ligase regulation of tissue-resident T cell and anti-tumor activity
Regulation of memory T cell differentiation and long-term maintenance
  • 批准号:
    10683278
  • 项目类别:
  • 资助金额:
    $55.53万
  • 财政年份:
    2020
  • 负责人:
    Ananda W Goldrath
  • 依托单位:
Regulation of memory T cell differentiation and long-term maintenance
  • 批准号:
    10591871
  • 项目类别:
  • 资助金额:
    $12.34万
  • 财政年份:
    2020
  • 负责人:
    Ananda W Goldrath
  • 依托单位:
Regulation of memory T cell differentiation and long-term maintenance
  • 批准号:
    10024589
  • 项目类别:
  • 资助金额:
    $50.91万
  • 财政年份:
    2020
  • 负责人:
    Ananda W Goldrath
  • 依托单位:
海外基金