ADMIN CORE

项目摘要/摘要(核心A：行政--行政管理) 行政核心(核心A，ADM)的主要职能是提供强有力的、一致的科学 领导能力，阐明和执行罗斯·F·肯尼迪科学方向的明确愿景 爱因斯坦/蒙特菲奥雷的国际数据中心。这是通过积极监督和评估4个科学 提供中心基本基础设施的核心，这些核心与中心紧密相连 与之相结合，我们的研究项目重点关注KDM5C疾病的智力障碍。ADM核心董事 (沃尔克利和莫尔霍尔姆博士)不知疲倦地在爱因斯坦/蒙特菲奥雷建立一个包容和充满活力的社区 专注于IDD研究。他们的行动是为了确保IDDRC调查人员优先访问这些科学 并持续监测核心利用率、质量控制和成本效益。他们还确保 通过定期监测和严格追求实现科学核心优化和现代化 年度调查。领导层促进中心及其调查人员的活动和成功 通过我们的网站、内部和外部出版物，包括年度 通过通讯和国家媒体渠道，并通过积极参与全国国际发展与发展中心网络。阿霉素 人员每年组织伊莎贝尔·拉宾关于传播障碍和国际的会议 罕见病日，以及专门的迷你讲习班，以促进研究人员合作和 社区外展。ADM核心也是连接基础科学实验室的主要外展机构，网址为 爱因斯坦与专注于IDD的诊所，包括蒙特菲奥雷儿童医院(Cham)和 爱因斯坦儿童评估和康复中心(CERC)。这是通过各种手段实现的， 包括我们的学院资助的试点资助计划，该计划吸引了新的研究人员进入IDD研究领域 并为与IDD相关的创新工作提供种子资金，以及我们的创新和非常成功的 精准医学项目被称为IDD基因团队行动。这些努力与我们的 新资助的IDD T32博士后培训补助金，本身已纳入正在进行的促进IDD的努力中 爱因斯坦医学系和研究生的参与和培训。RFK董事与他们的 由执行委员会领导该中心，并依赖其他常设委员会(内部和外部咨询 委员会和家庭咨询委员会)进行战略规划和反馈。URL在中的表示形式 我们位于布朗克斯的IDDRC在这里大力支持培训、教师招聘和病人招生。 通过坚定的领导和代表IDD研究的积极倡导，ADM核心积极 在爱因斯坦/蒙特菲奥里促进IDD相关基础、临床和转化研究的卓越表现。

PROJECT SUMMARY/ABSTRACT (Core A: ADMINISTRATIVE – ADM) The primary functions of the Administrative Core (Core A, ADM) are to provide strong, consistent scientific leadership and to enunciate and execute a clear vision for the scientific direction of the Rose F. Kennedy IDDRC at Einstein/Montefiore. This is achieved through active supervision and evaluation of the 4 scientific Cores that provide the fundamental infrastructure of the Center, and which are coupled to, and tightly integrated with, our Research Project focused on intellectual disability in KDM5C disease. ADM Core directors (Drs. Walkley and Molholm) work tirelessly to build an inclusive and vital community at Einstein/Montefiore focused on IDD research. They act to ensure prioritization of access by IDDRC investigators to these scientific Cores and consistently monitor Core utilization, quality control and cost effectiveness. They also ensure scientific Core optimization and modernization through regular monitoring as well as a rigorously pursued annual survey. The leadership promotes the activities and successes of the Center and its investigators through dissemination of IDDRC work via our website, internal and external publications including an annual newsletter and national media outlets, and through active participation in the National IDDRC Network. ADM personnel organize annually the Isabelle Rapin Conference on Communication Disorders and International Rare Disease Day, as well as specialized mini-workshops to promote investigator collaborations and community outreach. The ADM Core is also the major outreach arm that acts to connect basic science labs at Einstein with IDD-focused clinics, including those at the Children’s Hospital at Montefiore (CHAM) and the Children’s Evaluation and Rehabilitation Center (CERC) at Einstein. This is accomplished by various means, including our College-funded pilot grant program that draws new investigators into the field of IDD research and provides seed funds for innovative work related to IDD, as well as our innovative and highly successful program in precision medicine knows as Operation IDD Gene Team. These efforts are tightly coupled to our newly funded IDD T32 postdoctoral training grant which itself is integrated into ongoing efforts to foster IDD involvement and training of Einstein medical and graduate students. The RFK Directors work with their Executive Committee to lead the Center and rely on other standing committees (Internal and External Advisory Committees and Family Advisory Committee) for strategic planning and feedback. Representation of URMs in training, faculty recruitment and patient enrollment are strongly supported here in our Bronx-based IDDRC. Through committed leadership and vigorous advocacy on behalf of IDD research, the ADM Core aggressively promotes excellence in IDD-related basic, clinical and translational research at Einstein/Montefiore.