Diversity-focused Montefiore Einstein Clinical Oncology Training Program in the Bronx

项目摘要 爱因斯坦/蒙特菲奥雷·保罗·卡拉布雷西临床肿瘤学和公平奖职业发展奖的目标 研究是培养下一代肿瘤学学者，特别强调进行临床和 在服务不足和多样化的布朗克斯集水区进行翻译研究。这将通过一个 协调的指导计划、全面的正规课程和研究项目，以及 跨学科、协作性设计，注重社区外展和参与。该计划，其 领导力和参与者被整合到NCI指定的既定研究计划中 蒙特菲奥里·爱因斯坦癌症中心(AECC)。Calabresi计划将选择高质量的临床和 来自所有肿瘤学学科的转译研究人员，来自不同的群体，主要是医学博士，也有博士， 致力于以患者为导向的临床和转化性研究的职业，重点是多样化 人口。培训期限为2至3年，需要为4名学者提供资金。这项研究 重点正在从癌症治疗扩展到包括与布朗克斯相关的癌症护理服务 人口，占城市人口的70%。与爱因斯坦研究所联合开发了正式课程 临床和翻译研究(卢旺达问题国际法庭)，具有临床研究方法和硕士学位 包括两门以卡拉布雷西为中心的必修课程，其中一门课程的主题是 个性化癌症药物和免疫治疗“，以及关于”比较疗效治疗“的另一篇文章 研究“。此外，还开设了生物统计学和助学金写作方面的课程和研讨会。《校长》 调查人员是血液肿瘤科主任Amit Verma医学博士和Yvonne Saenger博士， 医学博士，免疫治疗项目主任和实验治疗学带头人。两个PI都带来了 在液体和固体肿瘤方面的互补专业知识，以及在基础/转换和临床方面的跟踪记录 研究，以及在指导初级临床研究人员方面。由高级教职领导组成的执行委员会 在学者的遴选和持续评估方面提供监督，并对 程序。由癌症中心主任朱博士担任主席的内部咨询委员会(IAB)和一名外部顾问 具有K12绩效指标的咨询委员会将为卡拉布雷西计划提供指导和指导。新颖的举措包括 计划增加市建局候选人的招聘。来自医学院的强有力的机构支持， 癌症中心和Montefiore得到了无数学者的工资支持。自成立以来，该计划 已招收24名学者(3名城市管理人员)：其余22名致力于学术生涯，担任领导职位 肿瘤学。高影响力出版物的成功记录，特别是在#年少数群体成果领域 布朗克斯多样化的人口是拟议培训计划独一无二的证据。我们建议的K12 培训基金将培训下一代肿瘤学临床研究人员，了解开展 使用布朗克斯作为模式生态系统，在服务不足的少数族裔人群中进行了成功的临床试验。

Project Abstract The goal of Einstein/Montefiore Paul Calabresi Career Development Award for Clinical Oncology and Equity Research is to train the next generation of oncology scholars, with a special emphasis on conducting clinical and translational research in the underserved and diverse Bronx catchment area. This will be achieved through a coordinated program of mentoring, a comprehensive formal curriculum, and research projects with an interdisciplinary, collaborative design with focus on community outreach and engagement. The program, its leadership and participants are integrated within the established research programs of the NCI-designated Montefiore Einstein Cancer Center (AECC). The Calabresi Program will select highly qualified clinical and translational investigators from all oncology disciplines, from a diverse group of primarily MDs, but also PhDs, who are committed to careers in patient-oriented clinical and translational research with a focus on diverse populations. The duration of the training is 2 to 3 years and funding for 4 scholars is requested. The research focus is being expanded beyond cancer therapeutics to include cancer care delivery relevant to the Bronx population, which is 70% URM’s. A formal curriculum has been developed in conjunction with Einstein’s Institute for Clinical and Translational Research (ICTR) featuring an MS degree in Clinical Research Methods and includes two mandatory Calabresi-centered courses, one on “Clinical Trial Development in the Era of Personalized Cancer Medicine and Immunotherapy”, and another on “Comparative Effectiveness Therapeutic Research”. Additional courses and workshops are offered in Biostatistics and Grant writing. The Principal Investigators are Dr. Amit Verma, M.D., Director of the Division of Hemato-Oncology, and Dr. Yvonne Saenger, MD, Director of the Immunotherapy program and Coleader of Experimental Therapeutics. Both PIs bring complementary expertise in both liquid and solid tumors and also a track-recordin basic/translational and clinical research, as well as in mentoring junior clinical investigators. An Executive Committee of senior faculty leaders provide oversight in the selection and ongoing evaluation of the progress of the Scholars and the impact of the program. An Internal Advisory Board (IAB) chaired by cancer center director, Dr. Edward Chu, and an External Advisory Board with K12 PIs will provide guidance and direction to the Calabresi program. Novel initiatives are planned to increase the recruitment of URM candidates. Strong institutional support from the Medical College, Cancer Center and Montefiorehas resultedin salary support of numerous scholars. Since inception, the Program has enrolled 24 Scholars (3 URMs): with 22 remaining committed to academic careers in leadership positions in oncology. A successful track record of high impact publications, especially in fields of minority outcomes in diverse populations of the Bronx is evidence of uniqueness of the proposed training program. Our proposed K12 training grant will train the next generation of oncology clinical researchers on unique challenges of conducting successful clinical trials in underserved minority populations, using the Bronx as a model ecosystem.