Biostatistics

项目总结/摘要 生物统计学共享资源（BiostatSR）支持Sidney Kimmel综合癌症 中心（SKCCC）确保研究设计、数据程序和研究数据分析采用最新技术 提供准确和可重现的研究结果总结的方法，包括相关的 不确定性，并帮助SKCCC研究人员获得同行评审的资金。BiostatSR成立于 1986年，作为共享资源获得了CCSG的第一笔资金。BiostatSR继续关闭 与SKCCC成员合作，提供研究设计、数据分析、监管和临时 报告（例如，数据安全性和监测报告）、手稿撰写和开发新的生物统计学 方法和研究设计所需的项目或受益于多个SKCCC研究者。BiostatSR 还支持创建信息系统，以支持个人或研究计划的努力。 除了与SKCCC的所有项目紧密结合外，BiostatSR生物统计学家还 重要的智力联系，以其他单位在约翰霍普金斯医学，如生物统计学系， 彭博公共卫生学院这种多样化的环境为SKCCC研究人员提供了强大的， 基础广泛的生物统计专业知识。 BiostatSR在当前的赠款周期内雇用了几名成员，并继续提供杰出的 支持SKCCC。在过去的资助周期中，BiostatSR继续与教职员工一起运作 与SKCCC研究计划和疾病组保持一致。BiostatSR成员参加定期会议 与他们的计划同事，并可在实验室研究和临床咨询 在这些项目中学习。例如，BiostatSR支持SPORE赠款和计划项目赠款 涉及教师和工作人员在临床前和翻译研究在许多领域。BiostatSR 成员们在编写案例报告方面加强了与研究协调员的合作 表格和方案特定数据库，以确保后续分析将忠实地呈现研究数据。 SKCCC托管共享资源 报告期：2020年1月1日至2020年12月31日

PROJECT SUMMARY/ABSTRACT The Biostatistics Shared Resource (BiostatSR) supports the Sidney Kimmel Comprehensive Cancer Center (SKCCC) to ensure that study designs, data procedures and analyses of study data use state-of-the-art methods that provide an accurate and reproducible summary of the study results, including associated uncertainties, and to help SKCCC researchers garner peer-reviewed funding. The BiostatSR, established in 1986, received its first CCSG funding as a Shared Resource that year. The BiostatSR continues close collaborations with SKCCC Members, providing expertise in study design, data analysis, regulatory and interim reporting (e.g., data safety and monitoring reports), manuscript writing, and development of new biostatistical methods and study designs required by a project or benefiting multiple SKCCC investigators. The BiostatSR also supports creation of information systems to support individual or Research Program efforts. In addition to being strongly integrated into all Programs in the SKCCC, BiostatSR biostatisticians have important intellectual ties to other units at Johns Hopkins Medicine, such as the Department of Biostatistics in the Bloomberg School of Public Health. This diverse environment provides SKCCC investigators with strong, broad-based biostatistical expertise. The BiostatSR hired several members during the current grant cycle and continues to provide outstanding support to the SKCCC. During this past funding cycle, the BiostatSR continued to function with faculty and staff aligned with SKCCC Research Programs and disease groups. BiostatSR members attend regular meetings with their programmatic colleagues and are available for consultation on laboratory investigations and clinical studies in those programs. For example, the BiostatSR supports SPORE grants and Program project grants involving faculty and staff in both preclinical and translational investigations in many areas. BiostatSR members have increased the level of collaboration with study coordinators in the development of case report forms and protocol-specific databases to ensure that subsequent analyses will faithfully present study data. SKCCC Managed Shared Resource Reporting Period: January 1, 2020 to December 31, 2020