Core A: Administrative Core

摘要-核心A：行政核心 行政核心(AC)的主要职能是：a)最大限度地扩大地方、全州和全国的影响 密歇根州民主与发展中心制定和实施的倡议；b)加强三方的合作 组成该联盟的伙伴大学(密歇根大学、韦恩州立大学和密歇根大学 与NACC、NCRAD和外部调查人员合作；c)提供健全的财政监督 和人事事项；以及d)确保所支持的研究和活动的严谨、完整和透明 在中间。咨询委员会稳定的领导层确保了各种研究、培训和外展计划 由核心管理的将保持与密歇根州ADRC的中心主题的协同和联系，这是 识别、了解和调节导致脑功能障碍和脑功能障碍的多种非β-淀粉样蛋白因子 阿尔茨海默病及相关痴呆的神经变性。咨询委员会将确保为所有人提供一个广泛支持的环境 调查人员，但特别是初级调查人员，目标是培养一批多样化的下一批- 世代领袖。为了发挥ADRC的最大作用，AC将与其他中心和 整个财团中从事与年龄相关研究的项目，包括六个由NIA资助的项目 这些中心共同组成了UMAging倡议。AC将在六个目标中：1)利用专家痴呆 专注于每个核心的资源和技能；2)保持核心之间的紧密互动；3)保持现有的 并建立新的地方和区域伙伴关系；4)维持现有的和进一步建立国家伙伴关系；5) 促进努力解决可持续发展中的种族和族裔差距；以及6)培养下一代领导人 通过不同的研究和培训机会。在其作为NIH指定的ADRC的第一个周期中，密歇根 ADRC达到了里程碑，部分原因是积极主动的AC帮助建立了关键的全州合作伙伴关系。 受益于与我们校园内许多由NIA资助的互补性项目的密切联系， 所有三所大学的杰出额外资源，以及持续的慈善成功，密歇根大学 ADRC处于有利地位，可以进一步丰富创新的痴呆症研究、推广和培训努力 在地区和全国范围内。

ABSTRACT – CORE A: ADMINISTRATIVE CORE The key functions of the Administrative Core (AC) are to: a) maximize the local, statewide and national impact of initiatives developed and implemented by the Michigan ADRC; b) enhance collaborations across the three partner universities comprising the consortium (University of Michigan, Wayne State University and Michigan State University) and with the NACC, NCRAD and outside investigators; c) provide sound oversight for fiscal and personnel matters; and d) ensure rigor, integrity and transparency in the research and activities supported by the center. The AC’s stable leadership ensures that the various research, training and outreach initiatives managed by the Cores will maintain synergy and connection to the Michigan ADRC’s central theme, which is to identify, understand and modulate the myriad non-β-amyloid factors that contribute to brain dysfunction and neurodegeneration in AD and related dementias. The AC will ensure a broadly supportive environment for all investigators, but particularly for junior investigators, with the goal of nurturing a diverse group of next- generation leaders. To have maximal effect as an ADRC, the AC will work closely with other centers and programs across the consortium that are engaged in age-related research, including the six NIA-funded centers that together comprise the UMAging Initiative. In six aims the AC will: 1) Leverage expert dementia resources and skills focused in each Core; 2) Maintain cohesive interplay across the Cores; 3) Sustain existing and build new local and regional partnerships; 4) Sustain existing and build further national partnerships; 5) Promote efforts to address racial and ethnic disparities in ADRD; and 6) Develop next-generation leaders through diverse research and training opportunities. In its first cycle as an NIH-designated ADRC, the Michigan ADRC met its milestones due, in part, to a proactive AC that helped build key state-wide partnerships. Benefitting from close links to the many complementary NIA-funded programs on our campuses, the outstanding additional resources of all three universities, and continuing philanthropic success, the Michigan ADRC is well-positioned to further enrich innovative dementia research, outreach, and training efforts, both regionally and nationally.