Physician Scientist Training in Cancer Research

总结 通过此竞争性续订申请，我们正在寻求五年的培训计划支持， 自2005年以来，“癌症研究中的医生科学家培训”的新头衔一直受到资助。 1975.从那时起，超过600名医生和医生科学家谁是奖学金培训的一部分， 通过这种资助机制，医学肿瘤学项目得到了必要的支持和保护， 这是他们开始学术生涯所需要的时间。在117名接受培训的学员中， 在过去15年的T32奖中，有13人继续作为博士后在培养。其余104人中， 离开学术界，在专注于癌症医学的行业中担任领导职务，6名是 主要的医疗中心，2人在国家癌症研究所任职，其余86人在学术界任职。 职位包括2名教授，22名副教授，39名助理教授和23名讲师。 除仍在接受培训的研究员外，其余104名前受训人员中有90人已获得外部资金， 他们的研究包括37项已被授予个人NIH K型奖。本 应用，我们寻求继续这一传统的培训领导人在学术肿瘤学。 癌症研究的未来将继续取决于对高素质人才的持续培训， 创造性的医生科学家谁拥有肿瘤疾病的临床方面的理解，是 能够将这些概念应用于肿瘤生物学许多领域内的适当实验室研究， 成为具有足够技能的学术领导者，以指导研究计划，病人护理和教育 努力这些人的发展只能在一个环境中完成， 医生和科学家在物理上相邻的地区工作，交流思想，在广泛的领域合作。 一系列的努力。该计划将建立在医学肿瘤学卓越的基础上， 在丹娜-法伯/马萨诸塞州布里格姆医学肿瘤学奖学金的临床培训期间， 程序.所有这些候选人都已经获得了医学博士或医学博士/博士学位，完成了2或3年的 内科住院医师，至少一年的肿瘤内科临床培训。 培训补助金计划将选择最高资格的候选人从这个池谁愿意 在Dana-Farber癌症研究所或附近进行实验室研究或临床研究 机构职能体系该计划将提供优秀的指导实验室和临床调查研究 来自资深和经验丰富的初级教师的经验，并支持招聘和指导 少数族裔研究员人数不足。预计在培训结束时，这些人 在此培训计划的支持下，将有能力设计，启动和完成个人临床或 实验室研究项目，将能够独立运作或最小的监督，并将 他们很快就能成为独立的研究人员。

Summary With this competitive renewal application, we are seeking five years of support for a Training Program with the new Title of “Physician Scientist Training in Cancer Research” that has been continually funded since 1975. Since that time, more than 600 physicians and physician-scientists who were part of fellowship training programs in medical oncology received, through this funding mechanism, the essential support and protected time that they required to launch an academic career. Of the 117 trainees who have been supported by this T32 Award during the past 15 years, 13 continue as post-doctoral fellows in training. Of the remaining 104, 10 have left academia to pursue leadership positions in industry focused on cancer medicine, 6 are clinicians at major medical centers, 2 hold positions at the National Cancer Institute, and the remaining 86 are in academic positions including 2 Professors, 22 Associate Professors, 39 Assistant Professors, and 23 Instructors. Excluding fellows still in training, 90 former trainees of the remaining 104 have received external funding for their research including 37 that have been awarded an individual NIH K-type award. With the present application, we seek to continue this tradition of training the leaders in academic oncology. The future of cancer research will continue to depend on the continued training of highly-talented and creative physician-scientists who possess an understanding of the clinical aspects of neoplastic disease, are able to apply these concepts to appropriate laboratory studies within the many areas of tumor biology and emerge as academic leaders with sufficient skills to direct research programs, patient care, and educational efforts. The development of such individuals can only be accomplished within an environment where physicians and scientists work in physically adjacent areas, exchanging ideas and collaborating on a wide array of endeavors. The program will build on a foundation of excellence in Medical Oncology established during clinical training in the Dana-Farber/Massachusetts General Brigham Medical Oncology Fellowship Program. All of these candidates have already received an MD or MD/PhD degree, completed 2 or 3 years of Internal Medicine residency, and at least one year of clinical training in Medical Oncology. The training grant program will select the most highly qualified candidates from this pool who wish to pursue laboratory research or clinical investigation at the Dana-Farber Cancer Institute or nearby surrounding institutions. The program will provide outstanding mentored laboratory and clinical investigation research experiences from senior and experienced junior faculty and support for the recruitment and mentorship of under-represented minority fellows. It is expected that at the conclusion of their training, those individuals supported by this training program will have the ability to design, initiate, and complete individual clinical or laboratory research projects, will be able to function independently or with minimal supervision, and will be positioned to soon establish themselves as independent research investigators.