Immunobiology of the Rheumatic Diseases

项目总结/摘要 本次应用是《风湿病免疫生物学》的竞争性更新 华盛顿大学医学院的培训项目。这个项目， 由约翰·阿特金森博士于1977年发起，在培养博士后研究员方面有着良好的记录， 致力于风湿病研究的职业。培训计划的目标是 培养独立的科学家，他们将最终致力于改善患者的预后， 风湿性疾病。目前的申请，寻求支持五个MD，MD/PhD，或 博士博士后培训生每年，纳入了一些新的方案特点， 加强这项训练使命。该计划接受来自扩大的人才库的学员， 优秀的申请人和受益于密切的关系，以医生科学家培训 医学和儿科课程，临床和转化科学研究所， 以及生物学和生物医学科学部。新的竞争性更新是 提供临床/转化研究轨道，补充我们的基础科学研究 轨道学员将受益于广泛的教学产品，导致科学硕士， 临床研究学位。无论是轨道的核心仍然是一个激烈的指导 研究经验。受训人员由一位忠诚的小学教师导师指导， 与奖学金监督委员会合作。由35名资金雄厚的 教师导师分为四个主题领域-免疫调节和宿主防御， 风湿病动物模型、临床/转化研究和组学。这些 导师是这项资助的主要力量。独特的协作环境， 教师和导师在WUSM提供了一个理想的环境，为专业发展 的学员。在负责任的国家举办的动手讲习班、研究研讨会和方案 研究的开展是对四个专题领域的补充。

PROJECT SUMMARY/ABSTRACT This application is the competitive renewal of the “Immunobiology of Rheumatic Diseases” Training Program at Washington University School of Medicine. The program, which was initiated in 1977 by Dr. John Atkinson, has a strong record of training postdoctoral fellows who are committed to careers in rheumatic disease research. The goal of the training program is to develop independent scientist who will ultimately work to improve outcomes of patients suffering from rheumatic diseases. The current application, which seeks support for five MD, MD/PhD, or PhD postdoctoral trainees per year, incorporates a number of new programmatic features to enhance this training mission. The Program accepts trainees from an expanded pool of outstanding applicants and benefits from close relationships to the Physician Scientist Training Programs in both Medicine and Pediatrics, the Institute of Clinical and Translational Sciences, and the Division of Biology and Biomedical Sciences. New to this competitive renewal is the offering of a clinical/translational research track which complements our basic science research track. Trainees will benefit from extensive didactic offerings leading to a Master of Science in Clinical Investigation degree. The centerpiece of either track remains an intense mentored research experience. Trainees are mentored by a committed primary faculty mentor, in collaboration with their scholarship oversight committee. The talented group of 35 well-funded faculty mentors are organized into four thematic areas- Immune Regulation and Host Defense, Animal Models of Rheumatic Disease, Clinical/Translational Research, and Omics. These preceptors are a major strength of this grant. The uniquely collaborative environment among the faculty preceptors and at WUSM provides an ideal setting for the professional development of the trainees. Hands on workshops, research seminars and programs in the Responsible Conduct of Research complement the four thematic areas.