Mechanisms Underlying Individual Variations of Taste and Smell in Obesity

该IRB批准的研究涉及肥胖和非肥胖个体之间的味觉和嗅觉测量的比较。味觉和嗅觉将根据其对食物摄入和食物选择的影响进行评估。我们假设肥胖会对味觉和嗅觉产生负面影响，从而影响饮食行为。我们将招募一组年龄和性别匹配的124名肥胖者和124名健康的非肥胖对照者。参与者将从华盛顿大都会区和附近地区招募。本研究将在NIH临床中心进行。本研究预计将在从开始入组至研究完成数据分析的60个月内完成。本研究包括1次筛选访视和2次研究访视。筛选访视将持续约4-5小时。访视1和访视2将分别需要约4-6小时才能完成。 目前正在招募

This IRB approved study involves comparison of taste and smell measures between obese and non-obese individuals. Taste and smell perceptions will be assessed in terms of their influence on food intake and food choices. We hypothesize that obesity negatively affects taste and smell perception thus affecting eating behavior. We will recruit a cohort of 124 obese individuals matched by age and sex with 124 healthy non-obese controls. Participants will be recruited from the Washington Metropolitan area and vicinity. This study will take place at the NIH Clinical Center. The study is expected to be completed in 60 months from opening of enrollment to study completion of data analysis. This study involves one screening visit and 2 study visits. The screening visit will last approximately 4-5 hours. Visits 1 and 2 will take approximately 4-6 hours each to complete. Currently enrolling