Penn Innovation in Suicide Prevention Implementation Research (INSPIRE) Center

这项建议是为了发展宾夕法尼亚大学在自杀预防方面的创新实施 研究(灵感)中心。在美国，自杀是主要的死亡原因，对 少数群体和被剥夺公民权的人口，包括黑人、西班牙裔和性/性别少数群体。然而，这些 群体通常不包括在自杀预防研究中。由概念模型指导，基于 集成行为模型，该模型假定组织文化、策略和资源(或缺乏) 影响提供者的属性和行为，INSPIRE将心理学、实施科学、 卫生经济学、机器学习、卫生信息技术、精神病学和参与性研究 专家们将创新的跨学科方法应用于自杀预防。INSPIRE的首要目标是 为服务不足的群体制定和调整以实践为基础的自杀预防干预措施，并 设计和测试实施策略，以优化循证实践如何规模化 高效和高保真，以实现最佳效果。Inspire将优先考虑那些可以快速 部署在一系列实践环境中，包括那些资源有限的环境，从而扩大其覆盖范围 以及对公共健康的影响。宾夕法尼亚大学INSPIRE将使用最先进的科学方法，从参与性研究到 积极吸引来自多个部门的利益相关者-包括患者、提供者和付款人-在各个级别 它的工作是为了实现其特定的目标。Inspire将应用创新、跨学科的行为改变和 开发、调整和评估成本效益干预措施的实施科学方法。签名 项目将使用阶梯式楔形研究设计来测试创新的组织战略， 远程医疗，在急诊科提供高质量的安全规划干预和后续服务。 三个探索性项目将测试新的自杀预防策略，覆盖个人、临床医生和 组织级别和特定的弱势群体，这将为更具确定性的 学习。Inspire还将支持10个试点项目和一个将开发和测试的创新方法核心 在自杀预防和实施科学的交叉点推进研究的新方法。这个 自杀预防学者计划将通过聘请这两个人来扩大自杀预防研究人员的队伍 目前没有从事自杀预防工作的新兴研究人员和老牌科学家--特别是 那些来自研究中代表性不足的群体--通过内容、设计。以及方法论指导和 能力建设。通过促进跨学科、跨部门的合作和推进自杀预防 在地方和国家的研究、关怀和政策方面，我们将开发具有成本效益、实用和高效的方式 实施循证自杀预防干预措施。Inspire准备为以下领域带来变革 防止自杀。

This proposal is to develop the University of Pennsylvania’s Innovation in Suicide Prevention Implementation Research (INSPIRE) Center. Suicide is a leading cause of death in the US that disproportionately affects minority and disenfranchised populations, including Blacks, Hispanics and sexual/gender minorities. Yet, these groups often are not included in suicide prevention research. Guided by a conceptual model based on the Integrated Behavior Model, which posits that organizational culture, policies, and resources (or lack thereof) impact the provider’s attributes and behaviors, INSPIRE brings together psychology, implementation science, health economics, machine learning, health information technology, psychiatry and participatory research experts to apply innovative interdisciplinary approaches to suicide prevention. INSPIRE’s overarching goals are to develop and adapt practice-based and other suicide prevention interventions for underserved groups and to design and test implementation strategies to optimize how evidence-based practices can be brought to scale efficiently and with high fidelity, for optimal effectiveness. INSPIRE will prioritize strategies that can be rapidly deployed in a range of practice settings, including those with limited resources, thereby increasing their reach and public health impact. Penn INSPIRE will use state-of-the-science methods from participatory research to actively engage stakeholders from many sectors – including patients, providers, and payers – at every level of its work to accomplish its Specific Aims. INSPIRE will apply innovative, interdisciplinary behavior change and implementation science methods to develop, adapt, and evaluate cost effective interventions. A Signature Project will use a stepped wedge study design to test an innovative organizational strategy that leverages telehealth to deliver high quality Safety Planning Intervention and follow-up services in Emergency Departments. Three Exploratory Projects will test novel strategies for suicide prevention across individual, clinician, and organizational levels and with specific vulnerable populations that will lay the foundation for more definitive studies. INSPIRE will also support 10 pilot projects and an innovative Methods Core that will develop and test new methods to advance research at the intersection of suicide prevention and implementation science. The Suicide Prevention Scholars Program will expand the cadre of suicide prevention researchers by engaging both emerging investigators and established scientists who do not currently work on suicide prevention – particularly those from groups under-represented in research – through content, design. and methodological mentoring and capacity-building. By catalyzing interdisciplinary, cross-sector collaborations and advancing suicide prevention research, care, and policy both locally and nationally, we will develop cost-effective, practical, and efficient ways to implement evidence-based suicide prevention interventions. INSPIRE is poised to be transformational for suicide prevention.