The Molecular Biology and Genotyping Core

摘要 分子生物学与基因分型核心 分子生物学和基因分型核心的目标是提高个体的能力 进行视觉科学研究的实验室，需要对小鼠模型进行基因分型并使用其他 分子生物学方法。因此，本单元的具体目标如下：1)提供 对小鼠基因分型进行集中定位和支持；2)培训研究人员并提供单独的实验室 在他们的分子生物学项目中得到帮助；以及3)提供培训和访问共享在核心 分子生物学和其他设备。此核心由经验丰富的人员运行，这有助于 VSRC调查人员高效地管理他们的老鼠窝，降低老鼠饲养成本，检测和 消除不受欢迎的突变，增加小鼠模型在研究中的实用性，并最终使其 科学具有更高的成本效益和生物学相关性。节省时间和资源的分子服务 生物学和基因分型核心对CASE的视觉研究人员具有重要的价值。

ABSTRACT The Molecular Biology and Genotyping Core The objective of the Molecular Biology and Genotyping Core is to enhance the capabilities of individual laboratories in conducting vision science research that requires genotyping of mouse models and use of other molecular biology methods. Accordingly, the Specific Aims of this Module are as follows: 1) to provide a centralized location and support for mouse genotyping; 2) to train researchers and provide individual laboratories with assistance in their molecular biology projects; and 3) to provide training and access to shared in the Core molecular biology and other equipment. The availability of this Core, run by highly experienced personnel, helps VSRC investigators to efficiently manage their mouse colonies, reduce the cost of mouse housing, detect and eliminate undesired mutations, increase the utility of mouse models in their research, and ultimately make their science more cost-efficient and biologically relevant. Time- and resource-saving services of the Molecular Biology and Genotyping Core are of great value to vision researchers at Case.