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中文摘要
翻译
血管风险因素与认知能力下降和痴呆有关,特别是在中年评估时。这些相同的风险因素是否决定了卒中后认知障碍的风险,这是一种血管风险普遍升高的情况,目前尚不清楚,其他可改变的风险因素的作用也不清楚。此外,血管对认知的影响机制是否仅仅是通过脑血管疾病(如小血管疾病,无症状梗死或微出血)的可识别的成像标志物,或者是否存在血管风险导致认知障碍的其他机制尚不清楚。SCAN部分正在进行的研究评估了VCID存在、病因学和潜在预防途径的相关问题。
英文摘要
Vascular risk factors are associated with cognitive decline and dementia, especially when evaluated in middle age. Whether these same risk factors determine risk of cognitive impairment after stroke, a condition where vascular risk is generally elevated, is not clear, nor is the role of other modifiable risk factors. Furthermore, whether the mechanism of a vascular impact on cognition is solely via identifiable imaging markers of cerebrovascular disease (such as small vessel disease, silent infarcts or microbleeds) or whether there are other mechanisms by which vascular risk contributes to cognitive impairment is not well understood. Ongoing studies in the SCAN section evaluate related questions to VCID presence, etiology, and potential pathways for prevention.
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DISCOVERY - Statistics and Analysis Core
  • 批准号:
    10021041
  • 项目类别:
  • 资助金额:
    $64.23万
  • 财政年份:
    2019
  • 负责人:
    Rebecca F Gottesman
  • 依托单位:
DISCOVERY - Statistics and Analysis Core
  • 批准号:
    10241403
  • 项目类别:
  • 资助金额:
    $64.23万
  • 财政年份:
    2019
  • 负责人:
    Rebecca F Gottesman
  • 依托单位:
DISCOVERY - Statistics and Analysis Core
  • 批准号:
    10709865
  • 项目类别:
  • 资助金额:
    $151.04万
  • 财政年份:
    2019
  • 负责人:
    Rebecca F Gottesman
  • 依托单位:
Neuroepidemiology of the vascular contribution to cognitive impairment and Alzheimer's disease
  • 批准号:
    9323230
  • 项目类别:
  • 资助金额:
    $16.05万
  • 财政年份:
    2016
  • 负责人:
    Rebecca F Gottesman
  • 依托单位:
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