The National Center for In-situ Tomographic Ultramicroscopy (NCITU)

项目摘要/摘要 设在纽约的国家原位断层超微中心(NCITU) 结构生物学中心，为用户提供准备标本的途径和服务 大分子联合和组织的直接可视化，特别是在天然细胞中。 一支高素质的技术团队可提供直接的实际服务、指导和帮助 确保样品和格子在最短的时间内以最高的质量准备好 有可能。 我们正在申请资金购买设备，以升级和扩大我们的计算能力 资源和升级我们的Thermo Fisher Science(TFS)Aquilos2，用于相关光和 电子显微镜(Clem)检查。这些升级将使NCITU的所有用户受益 这些工具的能力和能力。

Project Summary/Abstract The National Center for In-situ Tomographic Ultramicroscopy (NCITU), based at the New York Structural Biology Center, provides user access and service towards preparing specimens for direct visualization of macromolecular associations and organization, particularly in native cells. A highly qualified technical team provides direct hands-on service, guidance, and assistance to ensure that samples and grids are prepared with the highest quality and in the shortest time possible. We are requesting funds to purchase equipment to upgrade and expand our computational resources and upgrade our Thermo Fisher Scientific (TFS) Aquilos2 for correlative light and electron microscopy (CLEM) work. These upgrades will benefit all users of NCITU by increasing the capability and capacity of these instruments.