AIDS Subproject: Resveratrol Subproject 3
AIDS Subproject: Resveratrol Subproject 3
批准号:
10833987
负责人:
CHARLES HEBERT
金额:
$20.0万
依托单位国家:
美国
项目类别:
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-09-23 至 2023-09-22
关键词:
AIDS therapyAcquired Immunodeficiency SyndromeAdultAdverse effectsAnimalsBirthChemicalsDevelopmentDrug KineticsEnvironmental PollutantsExposure toFetal DevelopmentFlame RetardantsGoalsHIVHazardous ChemicalsHealthHumanIndustrializationInfertilityLaboratory RatLaboratory miceLifeMaterials TestingMusNational Institute of Environmental Health SciencesNational Toxicology ProgramOvaryPharmaceutical PreparationsPubertyRattusReproductionResveratrolRodentSafetyTestisTherapeuticToxic effectToxicity Testsabsorptionadverse outcomebody systemdesigndietary supplementsdisorder preventionearly life exposurepersonal care productspreclinical toxicityprenatal exposureprogramspublic health researchreproductive organreproductive toxicitysafety assessmenttrans-resveratroltumor
中文摘要
该项目的目标是为国家毒理学计划(NTP)的活动提供支持,以预防因暴露于化学或物理剂而引起的疾病或不良影响。毒性试验是公共卫生研究的一个重要方面,因为它有助于确定对人类健康有害的化学品。该计划旨在评估早期接触化学品后的毒性。
英文摘要
The goal of this project is to provide support of National Toxicology Program (NTP) activities targeted toward the prevention of diseases or adverse effects caused by exposure to chemical or physical agents. Toxicity testing is an important aspect of public health research in that it serves to identify chemicals that are hazardous to human health. This program is designed to evaluate toxicity following early life exposure to chemicals.
For this project, laboratory rats and mice are exposed to various test materials during fetal development and exposures may continue after birth and through adulthood. Animals are evaluated for adverse effects at different stages of life for effects such as changes in onset of puberty, infertility or other reproductive toxicity such as adverse effects on reproductive organs including ovaries or testes, and development of tumors or other adverse outcomes. Examples of chemical classes studied include personal care product ingredients, flame retardants, dietary supplements, industrial chemicals, environmental contaminants and drugs including AIDS therapies.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
IGF::OT::IGF Task Order #2 for "Continuous Rodent and Non-Rodent Pharmacokinetic Assessments"
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批准号:10022440
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项目类别:
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资助金额:$34.65万
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财政年份:2019
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负责人:CHARLES HEBERT
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依托单位:
IGF::OT::IGF TASK ORDER #001 PERFORMANCE AREA 1 MANAGEMENT AND OPERATIONS SUPPORT
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批准号:9785331
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项目类别:
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资助金额:$10.02万
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财政年份:2017
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负责人:CHARLES HEBERT
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依托单位:
IGF::OT::IGF TASK ORDER #001 PERFORMANCE AREA 1 MANAGEMENT AND OPERATIONS SUPPORT
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批准号:9376290
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项目类别:
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资助金额:$11.35万
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财政年份:2016
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负责人:CHARLES HEBERT
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依托单位:
IGF::OT::IGF CONTRACTOR ORIENTATION AND KICKOFF MEETING FOR SRI
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批准号:9161865
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项目类别:
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资助金额:$0.26万
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财政年份:2015
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负责人:CHARLES HEBERT
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依托单位:
AIDS Subproject 4
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批准号:10616454
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项目类别:
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资助金额:$40.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Subproject: Resveratrol Subproject 3
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批准号:10616453
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项目类别:
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资助金额:$40.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Subproject 4
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批准号:10833988
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项目类别:
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资助金额:$40.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Combination Therapy Subproject 2
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批准号:10616452
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项目类别:
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资助金额:$70.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Resveratrol Subproject 2
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批准号:10399955
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项目类别:
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资助金额:$70.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Tricombination Therapies Subproject 1
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批准号:9915363
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项目类别:
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资助金额:$240.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Combination Therapy Subproject 2
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批准号:10833986
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项目类别:
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资助金额:$22.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Tricombination Therapies Subproject 1
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批准号:10833985
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项目类别:
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资助金额:$18.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
Support of the Research Effort to Evaluate Toxicity Following Early Life Exposure to Test Articles for the NTP
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批准号:9315665
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项目类别:
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资助金额:$25.1万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
Other Projects, Deoxynivalenol Subproject 3
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批准号:9915365
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项目类别:
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资助金额:$21.54万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Tricombination Therapies Subproject 1
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批准号:10399954
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项目类别:
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资助金额:$70.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Subproject: Resveratrol Subproject 3
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批准号:10399956
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项目类别:
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资助金额:$50.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
IGF::OT::IGFSupport of the Research Effort to Evaluate Toxicity Following Early Life Exposure to Test Articles for the NTP
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批准号:8947879
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项目类别:
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资助金额:$400.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Resveratrol Subproject 2
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批准号:9915364
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项目类别:
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资助金额:$154.9万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
AIDS Tricombination Therapies Subproject 1
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批准号:10616451
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项目类别:
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资助金额:$70.0万
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财政年份:2013
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负责人:CHARLES HEBERT
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依托单位:
Preclinical Pharmacology and Toxicology Studies
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批准号:7891915
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项目类别:
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资助金额:$68.66万
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财政年份:2004
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负责人:CHARLES HEBERT
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依托单位:
海外基金