PROsIT: A Total Patient-Reported Outcomes Solution

描述（由申请人提供）：PROslT项目旨在通过跨学科努力开发和商业化一个全面、实用和集成的pro管理系统，促进患者报告结果（pro）在艾滋病临床和研究实践中的应用。它为用户可访问性和题库管理问题提供了创新的解决方案。具体的第一阶段目标是：1)开发基于项目反应理论（IRT）的自适应PROs评估引擎的原型，支持从网络和手机访问；2)从患者和医生的角度引出系统需求；3)识别临床环境中潜在的系统使用障碍。这项研究扩展了我们早期关于艾滋病和癌症的计算机结果解决方案的工作。将使用FAHI问卷。将与医生和患者进行焦点小组讨论，并与试点测试参与者进行面对面访谈，以评估系统可用性和有用性，改进需求，并确定潜在的障碍。PROslT是一种通用的结果收集、分析和报告解决方案，适用于艾滋病和其他疾病。它使研究人员能够通过接触更广泛的患者基础，进一步了解PROs在帮助临床决策方面的优势和局限性。它还广泛应用于制药公司、医院、保险公司、政府机构和认证组织。

DESCRIPTION (provided by applicant): The PROslT Project seeks to promote the use of Patient-Reported Outcomes (PROs) in both clinical and research practices for AIDS by developing and commercializing a comprehensive, practical and integrated system for PROs management with cross-discipline efforts. It offers innovative solutions to user accessibility and item bank management issues. The specific Phase 1 aims are to: 1) develop the prototype of an Item Response Theory (IRT)-based adaptive PROs assessment engine supporting access from both web and phones; 2) elicit system requirements from both patients' and physicians' perspectives; and 3) identify potential system usage barriers in clinical settings. This study extends from our earlier work on computerized outcomes solutions for AIDS and cancers. The FAHI questionnaire will be used. Focus group discussions with physicians and patients and face-to-face interviews with pilot-testing participants will be conducted to evaluate system usability and usefulness, refine requirements, and identify potential barriers. PROslT is a generic outcomes collection, analysis and reporting solution applicable to AIDS and other diseases. It enables researchers to further understand the strengths and limitations of PROs in helping clinical decisions by reaching to a broader patient base. It also has wide-ranging applications for pharmaceutical companies, hospitals, insurers, and government agencies and accreditation organizations.