Self-Caliberating Diagnostic Digital Radiometer

描述（由申请人提供）：拟议项目的总体目标是开发、制造和临床测试一种易于使用、价格合理的诊断仪器，该仪器可以无创地检测表面下炎症并估计炎症的温度。该仪器的设计将基于一种新型的快速读取、自校准、双频数字辐射计，该辐射计是在NIH的SBIR资助下开发的，用于二维非形热疗阵列天线。利用微波器件微型化的最新进展，辐射计的前端将与接收天线集成在一起。这将简化辐射计电路，提高其灵敏度，并减少校准和采集时间。检查卫生专业人员将能够像移动听诊器一样轻松地将小型集成天线组件（测温仪）移动到患者身体的任何一点，并快速准确地确定皮肤温度和两个不同组织深度的平均皮下组织温度。第一阶段计划的具体目标是设计、制造和测试一个装有Thermoseope的自校准诊断双频数字微波辐射计的实验模型，并为该辐射计编写软件，以增强其诊断功能。

DESCRIPTION (provided by applicant):The overall aim of the proposed program is to develop, fabricate and clinically test an easy-to-use affordable diagnostic instrument that can non-invasively detect subsurface inflammations and estimate the temperatures of such inflammations. The design of this instrument will be based on a novel fast-reading, self-calibrating, dual-frequency digital radiometer developed under an SBIR grant from NIH for use in two-dimensional eonformal hyperthermia array antennas. By taking advantage of recent advances in micro-miniaturization of microwave devices, the front-end of the radiometer will be integrated with the receiving antenna. This will simplify the radiometer circuitry, increase its sensitivity, and reduce calibration and acquisition times. The examining health professional will be able to move the small, integrated antenna assembly (Thermoscope) to any point on the body of a patient with the same ease as moving a stethoscope and quickly and accurately determine skin temperatures and two subsurface tissue temperatures averaged over two different tissue depth. The specific aims of the proposed Phase I program are to design, fabricate and test an experimental model of a Thermoseope equipped self-calibrating diagnostic dual-frequency digital microwave radiometer and write software for the radiometer that will enhance its diagnostic uefulness.