Developmental Research Program

项目总结/摘要 太平洋西北部（PNW）前列腺癌的发展研究计划（DRP）孢子是去- 签署了征求，评估和支持转化前列腺癌研究的创新试点项目。项目 在DRP资助下，旨在迅速推进一个新的想法或概念，有可能成为现实， 最终影响我们对前列腺癌的理解，并最终影响这一疾病的临床管理。 通过改进预防和治疗策略缓解。前列腺癌的早期症状有哪些？ DRP的基础设施SPORE建立了快速响应转化研究的机制 PNW SPORE机构内的机会，需要支持以推进假设或确认可行性， 为了证明更大的资源投资是合理的。发展项目包括基础科学研究， 临床科学和基于人群的研究，并将继续建立PNW SPORE之间的合作 研究中心和其他前列腺癌的SPORE机构。 发展研究计划的具体目标是： 1.促进创新，有影响力的早期研究的发展，包括多学科， 与PNW前列腺SPORE机构的基础、临床和人口科学家没有任何互动 包括孢子间的合作研究; 2.提供资金（1-2年）和基础设施（例如，生物标本，生物统计支持），以快速检测 在PC研究的所有领域中，最初的制造商发起的项目的可行性; 3.优先提供资金，以迅速利用新的机会或支持具有战略重要性的具体领域， 推进PNW前列腺孢子的转化研究目标; 4.推进早期科学研究，解决前列腺癌的健康差异，并促进再治疗。 由来自代表性不足的少数群体的科学家指导的搜索;以及， 5.监控（并促进）每个DRP项目的进展，并考虑将其推进到完整的SPORE 项目

PROJECT SUMMARY/ABSTRACT The Developmental Research Program (DRP) of the Pacific Northwest (PNW) Prostate Cancer SPORE is de- signed to solicit, evaluate, and support innovative pilot projects in translational prostate cancer research. Projects funded under the DRP are intended to rapidly advance a new idea or concept that has the potential to substan- tially impact our understanding of prostate cancer, and ultimately influence the clinical management of this dis- ease through improved prevention and treatment strategies. Since the inception of the PNW Prostate Cancer SPORE, the infrastructure of the DRP has established mechanisms to quickly respond to translational research opportunities within the PNW SPORE institutions that require support to advance hypotheses or confirm feasi- bility in order to justify larger resource investments. Developmental projects include research in basic science, clinical science, and population-based studies, and will continue to build collaborations between PNW SPORE sites and other institutions with SPOREs in prostate cancer. The Specific Aims for the Developmental Research Program are to: 1. Stimulate the development of innovative, impactful early-phase research studies that include multi-discipli- nary interactions with basic, clinical, and population scientists across the PNW Prostate SPORE institutions and including inter-SPORE collaborative studies; 2. Provide funding (1-2 years) and infrastructure (e.g., biospecimens, biostatistical support) to rapidly test the feasibility of original investigator-initiated projects in all areas of PC research; 3. Prioritize funding to rapidly exploit new opportunities or support specific areas of strategic importance for advancing the translational research goals of the PNW Prostate SPORE; 4. Advance early stage scientific research that addresses prostate cancer health disparities and promote re- search directed by scientists from underrepresented minority groups; and, 5. Monitor (and facilitate) the progress of each DRP project and consider their advancement to a full SPORE project.