Endocrine Scientist Training Program

描述（由申请人提供）： 内分泌和代谢紊乱在美国很普遍。以前在中年和老年人中发现的2型糖尿病现在在年轻人和儿童中迅速发展。一种在越来越年轻的人群中赋予高心血管风险的疾病的发作对公共卫生具有惊人的影响。此外，随着美国人口老龄化，增加心血管风险的其他疾病（高血压、血脂异常、肥胖）和其他常见的衰老疾病（如骨质疏松症）消耗了越来越大比例的医疗保健支出。要解决这些难题，不仅需要培养足够数量的医生来照顾受影响的病人，而且还需要培训熟练的研究人员，以开发创新疗法和预防措施，并深入研究疾病的基本机制。印第安纳州大学医学院是医学的许多领域的领导者。它的儿科内分泌学和糖尿病科以及医学系内分泌学和代谢科都是备受尊敬的大型研究部门，具有指导博士前和博士后学员的悠久历史，包括在儿科和成人内分泌学的研究中相互培训研究员。拟议的内分泌科学家培训计划为儿科，成人或联合医学-儿科内分泌学培训的年轻科学家提供了机会，以提高他们在基础实验室，临床或转化研究中的技能，从而成为独立的学术研究人员。完成住院医师培训后，高素质的医生将进入内科，儿科内分泌学或联合医学-儿科奖学金，接受相应学科的临床培训，然后进入两个轨道之一的联合计划，内分泌学轨道的基础科学或内分泌学临床研究轨道。这些轨道提供广泛的直接和教学研究培训。该计划将培养内分泌学领域的顶尖医生科学家，他们将从事尖端研究，为美国人民的健康做出重大贡献。通过这次重新提交，我们借此机会加强了研究培训计划。它提供了一种独特和创新的培训方法，并在我们成功的历史基础上利用现有的特殊机构资源

DESCRIPTION (provided by applicant): Disorders of endocrinology and metabolism are prevalent in the U.S. Type 2 diabetes, previously found in middle aged and elderly adults, is now burgeoning in young adults and children. The onset of a disease that imparts high cardiovascular risk in ever-younger populations has staggering implications for public health. In addition, as the U.S. population ages, other disorders that increase cardiovascular risk (hypertension, dyslipidemia, obesity) and other common disorders of aging, such as osteoporosis, consume ever-larger proportions of health care expenditures. Addressing these difficult dilemmas requires not only the development of a critical mass of physicians to care for affected patients, but also the training of skilled researchers to develop innovative therapies and preventive measures and to delve into the basic mechanisms of diseases. The Indiana University School of Medicine is a leader in many fields of medicine. Its Section of Pediatric Endocrinology and Diabetes and the Division of Endocrinology and Metabolism in the Department of Medicine are both large well respected research divisions with a long history of mentoring pre- and postdoctoral trainees, including training one another's fellows in research that spans the spectrum of pediatric and adult endocrinology. The proposed Endocrine Scientist Training Program provides the opportunity for young scientists in Pediatric, Adult, or Combined Medicine-Pediatric Endocrinology training to enhance their skills in either basic laboratory, clinical, or translational research, leading to careers as independent academic researchers.-After completion of their residency training, highly qualified physicians will enter either the Internal Medicine, Pediatric Endocrinology, or combined Medicine-Pediatrics fellowship, receive clinical training in the respective discipline(s), then enter this combined program in one of two tracks, the Basic Science of Endocrinology Track or the Endocrinology Clinical Research Track. These tracks provide extensive direct and didactic research training. This program will train top-notch physician scientists in the field of Endocrinology who will engage in cutting-edge research to make major contributions to the health of the American people. With this resubmission, we have taken the opportunity to enhance the research training program. It provides a unique and innovative approach to training, and it puts the exceptional institutional resources now available to use, building on our history of success