Capacity Development Core

建立成功的研究合作具有挑战性。成功的合作更具挑战性 在跨机构和与早期研究者（ESI）合作时。为了克服这些挑战，我们 发展核心能力建设。核心的目标是提供资源和指导， 希望之城综合癌症中心（CoHCCC）和加州大学之间的合作， 滨江（UCR）ESI。我们的目标是建立合作，1）提高UCR的药物开发能力 能力-在药物开发管道的所有阶段和2）导致独立的NIH资金。的能力 核心将匹配UCR ESI与高级CoHCCC和UCR调查员。CoHCCC高级研究员将 根据他们先前证明的以下能力进行选择：1）成功指导ESI，2）帮助他们实现独立 NIH资助。U 54 PI，Ernest Martinez博士（UCR）和维多利亚Seewaldt博士（CoH）有广泛的指导 经验，并将领导能力的核心。在能力核心下，UCR-CoH迷你飞行员将由 在高级指导下的ESI，2）参加比赛，3）团队获得一年10万美元的奖励。我们的P20规划 格兰特告诉我们，当ESI有来自CoH和 UCR;因此，申请迷你飞行员的UCR ESI需要有CoH和UCR导师。在第一年和 2每年将资助3个小型试点项目。这6个迷你飞行员将是我们建立 联合UCR ESI-CoH赠款和UCR的能力。在第3-5年，200，000美元最初分配给能力 建筑核心，将重新分配，以支持两个新的试点-试点3和4。在第3-5年，我们将提供1个迷你- 飞行员/年CoH自由支配资金（100，000美元/年）将允许我们补充试点项目或增加 3-5年级提供的迷你飞行员数量。

It is challenging to build successful research collaborations. Successful collaborations are even more challenging when working across institutions and with early-stage investigators (ESIs). To overcome these challenges, we developed the Capacity Building Core. The Core's goal is to provide resources and mentorship to build joint collaborations between City of Hope Comprehensive Cancer Center (CoHCCC) and University of California, Riverside (UCR) ESI. We aim to build collaborations that 1) increase UCR capacity for drug development capacity - at all stages of the drug-develop pipeline and 2) result in independent NIH-funding. The Capacity Core will match UCR ESIs with senior CoHCCC and UCR investigators. Senior CoHCCC investigators will be selected based on their prior proven ability to 1) successfully mentor ESIs and 2) help them attain independent NIH funding. U54 PI, Drs. Ernest Martinez (UCR) and Victoria Seewaldt (CoH) have extensive mentorship experience and will lead the Capacity Core. Under the Capacity Core, UCR-CoH Mini-Pilots will be 1) crafted by ESIs under senior mentorship, 2) competed, and 3) teams awarded $100,000 for one year. Our P20 planning grant shows us that success of a pilot project is increased when ESI have senior mentors from both CoH and UCR; therefore UCR ESI applying for Mini-Pilots are required to have a CoH and UCR mentor. In Years 1 and 2 a total of 3 Mini-Pilots will be funded/year. These 6 Mini-Pilots will be an important opportunity for us to build joint UCR ESI-CoH grants and capacity at UCR. In Years 3-5, $200,000 originally allocate to the Capacity Building Core, will be re-allocated to support two new Pilots – Pilots 3 and 4. In Years 3-5, we will offer 1 Mini- Pilot/year. CoH discretionary funds ($100,000/year) will allow us to either supplement Pilot Projects or increase the number of Mini-Pilots offered in Years 3-5.