High energy density film capacitors for Compact Implantable Cardioverter Defibril
High energy density film capacitors for Compact Implantable Cardioverter Defibril
批准号:
7399754
负责人:
Shihai Zhang
金额:
$9.87万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-03-01 至 2008-08-31
关键词:
Acquired Immunodeficiency SyndromeAluminumAmericanAnti-Arrhythmia AgentsAreaArrhythmiaChargeChestClinical TrialsCommitConditionDevelopmentDevicesElectric CountershockElectrodesElectronicsExternal DefibrillatorFigs - dietaryFilmHeartHeart ArrestHeart failureHourImplantImplantable DefibrillatorsIndividualLettersLifeLiquid substanceMalignant neoplasm of lungManufacturer NameMedicalMiniaturizationMonitorOperative Surgical ProceduresPatientsPennsylvaniaPerformancePhasePhysiologic pulsePlant ResinsPolymersProcessPrunella vulgarisPulse takingSaint Jude Children&aposs Research HospitalScienceSeriesSignal TransductionSmall Business Funding MechanismsSmall Business Innovation Research GrantSpeedTantalumTechnologyTestingThickTimeTranslatingUniversitiesWeightWorkbasecostdaydesireenergy densityfootheart rhythmimprovedmalignant breast neoplasmmortalityprofessorprogramsprototypesensorsizesudden cardiac deathvoltage
中文摘要
描述(由申请人提供):每天有超过1000名美国人死于心脏骤停(SCA),其夺去的生命比乳腺癌、艾滋病和肺癌加起来还要多植入式心律转复除颤器(ICD)可以提供24小时心律监测并提供即时有效的治疗,因此可以将总死亡率降低23%,并为患者提供2.5年以上的生命。然而,目前ICD的尺寸、成本和可靠性限制了其被患者接受。电容器作为关键部件,占据ICD容积的1/3以上,向心脏输送必要的除颤能量。战略聚合物科学公司(SPS)开发了一系列新的极性氟聚合物电介质,其能量密度(25 J/cm3)至少比目前的ICD电容器(4-6 J/cm3)高4倍,比其他聚合物薄膜电容器(< 2 J/cm3)高10倍,因此它们可以显着减小ICD的尺寸和重量(Science 313:334(2006),“具有高电能密度和快速放电速度的介电聚合物”)此外,SPS介电聚合物具有自愈特性,不含任何液体,不需要定期重整,因此可以提高ICD的可靠性,延长电池寿命。SPS正在与电容器和ICD制造商合作,将这些新材料商业化。
英文摘要
DESCRIPTION (provided by applicant): More than 1000 Americans die every single day due to sudden cardiac arrest (SCA), which claims more lives than breast cancer, AIDS, and lung cancer combined.1 Implantable Cardioverter Defibrillators (ICD) can provide 24-hour monitoring of heart rhythm and deliver immediate effective treatment, thus can reduce overall mortality by 23% and provide 2.5 more years of life for a patient. However, the size, cost, and reliability of current ICD limit its acceptance by the patients. As a key component, the capacitor occupies more than 1/3 of the ICD volume and delivers the necessary defibrillation energy to the heart. Strategic Polymer Sciences, Inc (SPS) has developed a series of new polar fluoropolymer dielectrics that have energy density (25 J/cm3) at least four times higher than the current ICD capacitors (4-6 J/cm3) and ten times higher than other polymer film capacitors (< 2 J/cm3), therefore they can significantly reduce the size and weight of ICD (Science 313:334 (2006), "A dielectric polymer with high electric energy density and fast discharge speed").6 In addition, SPS dielectric polymers have self-healing feature, do not contain any liquid, do not require regular reforming, thus can improve the reliability of the ICD and extend the battery life. SPS is working with both capacitor and ICD manufacturers to commercialize these new materials.
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