EFFECT OF RELOCATION ON NIGHTTIME ACTIVITY AND STRESS RESPONSES IN MACAQUES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 自伤行为(SIB)是一个重要的人类健康问题，在青少年中呈上升趋势。在正常饲养的单独饲养的成年雄性恒河猴中，有一小部分会自发地发展出自我伤害行为(SIB)。在这个子项目中，我们研究了搬迁应激对患有和不患有SIB的恒河猴的行为和下丘脑-垂体-肾上腺功能的短期和长期影响。动物们被转移到了一栋新的大楼里，那里有不同的笼子和新的室友，这些变化预计会带来压力。行为评估在白天和晚上进行，并在行动之前、之后不久和一年后收集血浆、唾液和头发样本。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Self-injurious behavior (SIB) is a significant human health problem which is on the rise among teenagers and young adults. A small percentage of normally reared, individually housed adult male rhesus monkeys spontaneously develop self-injurious behavior (SIB). In this subproject, we examined the short- and long-term effects of a relocation stress on behavior and hypothalamic-pituitary-adrenal function in rhesus monkeys with and without SIB. The animals were moved to a new building with different caging and new roommates, changes that were expected to be stressful. Behavioral assessments were conducted during daylight and evening hours, and samples of plasma, saliva, and hair were collected before, shortly after, and 1 year following the move.