Training in Older Adult Mobility Research

描述(由申请人提供)：在最初的K24奖励期间，PI的研究生产力和导师的深度和广度都得到了提高和加速。在几位受训者的投入和努力下，研究活动已经超越了以前关注的生物力学、姿势控制和功能活动，转向了新的感兴趣领域，包括：1)对未受损和受损的老年人(包括充血性心力衰竭和2型糖尿病患者)的有氧评估和干预；2)在这些人群中增加对加强体力活动的坚持；3)创新的阻力训练形式和肌肉功能变化的潜在机制；4)身体损伤与环境之间的接口；以及5)制定计划，将干预策略，特别是与降低跌倒风险相关的干预策略，转化到社区中。K24奖项有助于为PI提供受保护的时间，让他们参与广泛的地方、国家和国际指导和领导机会。PI能够利用他在密歇根大学和弗吉尼亚州安娜堡GRECC广泛的培训计划基础设施中的参与，扩大他的指导活动的质量和数量。持续的K24支持将实现以下目标：1)在老年人行动方面进一步建立以患者为导向的独立和协作的临床研究计划。2)继续临床研究领导活动，并将高级导师的角色扩大到其他初级导师。3)为更多从事老年人活动能力临床研究的多学科受训人员提供指导。4)进一步探索与移动相关的转化研究机会，在社区中架起基础科学、临床和应用项目的桥梁。简而言之，持续的K-24支持对于PI扩大和保持他作为导师的角色至关重要，为更多的多学科受训人员提供各级培训的指导，并进一步探索与行动相关的翻译研究，从而将行动研究中心建立为老年人临床行动研究培训的首要项目。这项由K-24奖项推动的研究和培训计划不仅将推动老年人行动能力评估和增强领域的发展，而且还将提供一批未来的领导者来继续这一进步。

DESCRIPTION (provided by applicant): During the initial K24 award period, the Pi's research productivity and mentorship increased and accelerated in depth and breadth. With the input of and work of several mentees, research activities have moved beyond a previous focus of biomechanics, postural control, and functional mobility to new areas of interest including: 1) aerobic assessments and interventions in unimpaired and impaired older adults (including those with congestive heart failure and Type 2 diabetes mellitus); 2) strategies to increase adherence to enhancing physical activity in these populations; 3) innovative forms of resistance training and the mechanisms underlying change in muscle function; 4) the interface between physical impairment and the environment; and 5) development of programs to translate intervention strategies, particularly related to fall risk reduction, into the community. The K24 award has been instrumental in giving the PI the protected time to participate in a wide range of local, national, and international mentorship and leadership opportunities. The PI has been able to leverage his participation in the extensive training program infrastructure at the University of Michigan and the Ann Arbor VA GRECC to broaden the quality and quantity of his mentorship activities. Continued K24 support will achieve the following objectives: 1) To further establish an independent and collaborative patient-oriented clinical research program in older adult mobility. 2) To continue the Pi's clinical research leadership activities and broaden his role as a senior mentor to other junior mentors. 3) To provide mentorship to a widening group of multidisciplinary trainees pursuing clinical investigation of mobility in older adults. 4) To further explore mobility-related translational research opportunities bridging basic science, clinical, and applied programs in the community. In short, continued K-24 support is critical for the PI to broaden and sustain his role as a mentor, to provide mentorship to a widening group of multidisciplinary trainees at various levels of training, and to further explore mobility-related translational research, thereby establishing the Mobility Research Center as the premier program for training in clinical mobility research for older adults. The program in research and training facilitated by this K-24 award will not only advance the field of mobility assessment and enhancement in older adults but also provide a cadre of future leaders to continue this progress.