NEURODEVELOPMENTAL ASSESSMENT OF ELBW INFANTS: USE ASQ PARENT QUESTIONNAIRES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 近50%的极低出生体重儿（ELBW）在18至22个月校正年龄时有异常的神经发育和/或感觉发现。 早期识别不良发育后遗症不仅对确定托儿所药物治疗的中长期影响很重要，而且对通过早期干预解决潜在发育迟缓和残疾提供最佳机会也很重要。 正式的发展测试是昂贵的，可能是有限的，其可用性以外的大都市地区，使系列正式评估不切实际。 当父母对孩子目前的行为和发展的投入被引出时，专业管理的发展筛查和评估的准确性得到了提高。 年龄和阶段问卷（ASQ），家长管理的发展筛选工具，可能是一个具有成本效益的替代昂贵的，系列专业管理的发展评估。 本项目的具体目标是：1）由父母管理的ASQ在4个年龄点确定的发展趋势（4、8、12和18个月矫正年龄），预测在18-22个月矫正年龄时通过正式的、专业管理的发育测试获得的结果; 2）由父母进行的18-22个月校正年龄ASQ的结果与专业评估结果之间的关系。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Nearly 50% of extremely low birth weight (ELBW) infants have abnormal neurodevelopmental and/or sensory findings at 18 to 22 months adjusted age. The early identification of adverse developmental sequelae is important not only to ascertain the medium and long-term effects of medical therapies in the nursery, but also to afford the best opportunity for addressing potential developmental delays and disabilities with early interventions. Formal developmental testing is expensive, and may be limited in its availability outside of metropolitan areas, making serial formal evaluations impractical. The accuracy of professionally administered developmental screenings and assessments is enhanced when parent input regarding a child's current behavior and development is elicited. The Ages and Stages Questionnaire (ASQ), a parent-administered developmental screening tool, may be a cost-effective alternative to expensive, serial professionally administered developmental evaluations. The specific goals of this project are to examine: 1) if developmental trends, as determined by the parent-administered ASQ at 4 age points (4, 8, 12, and 18 months corrected age), predict the results obtained on formal, professionally administered developmental testing at 18-22 months corrected age; and 2) the relationship between the results of the 18-22 month corrected age ASQ, administered by parents, with the results of this professionally administered evaluation.