Microtubule stabilisation: promoting adaptive plasticity, brain healing and functional recovery after traumatic brain injury

创伤性脑损伤(TBI)仍然是45岁以下人群死亡和残疾的主要原因。目前还没有有效的药物治疗方法能够预防或最大限度地减少脑损伤。我的团队将使用复杂的体内技术来充分描述大脑对损伤的反应，并测试通过新一代紫杉醇类药物稳定微管是否会改善创伤后的结果。

Traumatic brain injury (TBI) continues to be the leading cause of death and disability for individuals under 45 years of age. There are currently no effective pharmacotherapeutics available that are able to prevent or minimise brain damage following TBI. My team will use sophisticated in vivo techniques to fully characterise the brain's response to injury and to test whether microtubule stabilisation via new generation taxol-like drugs improves post-trauma outcomes.