THE EFFECTS OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART)

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 艾滋病毒通过感染体内许多不同类型的血细胞来破坏免疫系统。一些受感染的细胞应该通过帮助对抗感染（如艾滋病毒）来保护身体免受疾病的侵害。当这些细胞被感染时，它们无法抵抗感染，最终细胞死亡。结果，孩子的免疫系统变弱。 当一个孩子服用治疗艾滋病毒感染的药物组合（HAART）时，病毒不能快速繁殖，免疫系统的细胞可以帮助对抗感染。这项研究的目的是告诉有多少免疫细胞返回，以及血液中的艾滋病毒的数量，而他/她是HAART。为了研究儿童的免疫系统，他/她将接受FDA批准的两种不同的儿童疫苗。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. HIV damages the immune system by infecting many different types of blood cells in the body. Some of the infected cells are supposed to protect the body from disease by helping to fight infections, such as HIV. When these cells become infected, they are not able to fight infections and eventually the cells die. As a result, a child's immune system gets weak. When a child takes a combination of drugs for the treatment of HIV infection (HAART), the virus is not able to multiple as quickly and the cells of the immune system can help fight infection. The purpose of this study is to tell how many immune cells return, and the amount of HIV in the blood while he/she is on HAART. In order to study a child's immune system, he/she will receive two different vaccines which are approved by the FDA for children.