GENETIC EPIDEMIOLOGY OF ENERGY METABOLISM

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是为了更好地了解基因如何影响12名16岁的非裔美国女孩的静息能量消耗，这可能有助于青春期肥胖的发展。这项研究分为两个部分。最初，我们将对1000名女孩进行口腔筛查，进行基因分型。那些与我们感兴趣的特定基因匹配的人将被要求来辛辛那提儿童医院医学中心的普通临床研究中心过夜。在过夜的访问中，受试者将测量身体成分，如身高、体重和皮褶。受试者还将接受DXA扫描、抽血和静息能量测试。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to better understand how genes may influence resting energy expenditure in 12  16 year old African American girls which may contribute to the development of obesity during adolescence. There are two parts to the study. Initially, we will buccal screen 1000 girls for genotyping. Those that are a match the specific genes we are interested in, will be asked to come for an overnight visit at Cincinnati Children's Hospital Medical Center's General Clinical Research Center. At the overnight visit, the subject will have measurements of body composition such as height, weight and skinfolds. The subject will also have a DXA scan, blood draw, and a Resting Energy test.