Minimally-invasive gene delivery of a novel inhibitor of retinal angiogenesis

眼睛血管的过度生长会导致视力丧失，只能通过激光或疼痛和频繁的眼睛注射来治疗。Vasostatin是一种特异性的血管生成抑制剂，是一种有前途的治疗眼部新生血管的药物。我们将提供临床前证据，表明血管抑制素样肽的基因递送是一种有效的治疗策略，它有可能彻底改变目前的年龄相关性黄斑变性的眼科护理。

Excessive growth of blood vessels in the eye causes vision loss and can only be treated with lasers or painful and frequent injections into the eye. Vasostatin is a specific inhibitor of angiogenesis and a promising agent for the management of ocular neovascularisation. We will provide pre-clinical evidence that gene delivery of vasostatin-like peptides is an effective therapeutic strategy and it has potential to revolutionize the current ophthalmic care of age-related macular degeneration.