CORE--CELL BIOLOGY

细胞和分子神经科学与神经遗传学 Jean de Vellis和Anthony Campagnoni，小组协调员 在过去的十年里，由Jean de Vellis和Anthony领导的研究小组 Campagnoni越来越多地采取类似的方法来调查潜在的 指导神经系统正常发育的机制以及 导致发育障碍的发病机制，即精神发育迟滞和发育障碍 残疾（MRDD）。他们利用遗传学，分子生物学，细胞和分子 神经科学来分析人类基因工程动物模型的机制 发育障碍MRRC的大多数研究人员都是 对神经系统的发展很感兴趣另一个原因是， 坎帕尼奥尼和德韦利斯集团在一起的原因是，他们将搬到三楼的 早春的神经科学研究/MRRC大楼。他们建立了共享治理， 利用大型共享实验室、手术室、动物园和大型线性设备室。 因此，他们希望在努力阐明 神经生物学和发育障碍遗传学。一些遗传学家已经 位于附近的人类遗传学系。一个共同的研究兴趣是 干细胞的研究，一个与最近加州倡议相关的领域， 补充资金。哈雷科恩布卢姆是新兴神经干细胞中心的主任， 被招募为MRRC核心教师和精神病学和生物行为科学将 成为他的主要部门。Kornblum加入了Sun，Fan，Waschek，de Vellis和Cederbaum 他们对干细胞在发育和MRDD中的作用非常感兴趣。研究 这两组的进展由研究者按顺序列出。

CELLULAR AND MOLECULAR NEUROSCIENCE AND NEUROGENETICS Jean de Vellis and Anthony Campagnoni, Group Coordinators During the last decade, the research groups headed by Jean de Vellis and Anthony Campagnoni have increasingly taken similar approaches to investigate the underlying mechanisms directing the normal development of the nervous system as well as the pathogenesis causing developmental dysfunctions, i.e. mental retardation and developmental disabilities (MRDD). They use genetics, molecular biology, and cellular and molecular neuroscience to analyze mechanisms in genetically-engineered animal models of human developmental disorders. The majority of MRRC researchers throughout this group are interested in the development of the nervous system. Another reason to present the Campagnoni and de Vellis groups together is that they will move to the third floor of the Neuroscience Research/MRRC Building in early spring. They have set up shared governance to utilize large shared laboratories, procedure rooms, vivarium, and a large linear equipment room. Therefore they expect to generate more collaborations in their efforts to elucidate the neurobiology and genetics of developmental disorders. Some of the geneticists are already located in the nearby Department of Human Genetics. One of the common research interests is the study of stem cells, an area relevant to the recent California initiative that will hopefully supplement funding. Harley Kornblum, the director of the budding Neural Stem Cell Center has been recruited as an MRRC core faculty and Psychiatry and Biobehavioral Sciences will become his primary department. Kornblum joins Sun, Fan, Waschek, de Vellis and Cederbaum who have major interest in stem cells for their role in development and MRDD. The research progress for these two groups is listed alphabetically by investigator.