CELLULAR AND MOLECULAR NEUROSCIENCE CORE

引言 细胞和分子神经科学(CMN)的核心是从以前的病理学、组织学和 立体学(PHS)核心。新的核心反映了服务的重组、重新定位和扩展。这个 重组反映了领导层的更迭，医学博士詹姆斯·马尔特在 2003年，随着核心活动的变化和重点从主要的形态服务 (例如，组织病理学、玻片制备和电子显微镜)到与当代更相关的学科 细胞和分子神经科学。服务的扩展反映了新的最先进的 设备(例如，共焦显微镜和荧光显微镜、流式细胞仪、磷成像和实时聚合酶链式反应) 和专业知识(例如，DMA基因阵列、蛋白质组学和病毒载体生产)。因此，新的 CMN Core并不是表面上的重组，而是对一系列新服务、设备和 支持MRDDRC分子和遗传科学小组不断变化的需求和组成 (MGSG)。

INTRODUCTION The Cellular and Molecular Neuroscience (CMN) Core grew out of the former Pathology, Histology and Stereology (PHS) Core. The new Core reflects a reorganization, refocusing, and expansion of services. The reorganization mirrors a leadership change, with James Malter, MD, assuming the position of Core Director in 2003, along with a change and refocusing in the Core's activities from predominantly morphologic services (e.g., histopathology, slide preparation, and electron microscopy) to those more relevant to contemporary cellular and molecular neuroscience. The expansion of services reflects the addition of new state-of-the-art equipment (e.g., confocal and fluorescence microscopy, flow cytometry, phosphorimaging, and real time PCR) and specialized expertise (e.g., DMA gene arrays, proteomics, and viral vector production). Thus, the new CMN Core is not a cosmetic reshuffling but a true commitment to a host of new services, equipment, and support for the changing needs and composition of the MRDDRC Molecular and Genetic Sciences Group (MGSG)oftheMRDDRC.