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中文摘要
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描述(由申请者提供):从事临床研究的医生数量下降,引发了全国对公共卫生保健即将到来的危机的担忧。虽然许多医学领域都受到了影响,但精神病学的问题尤其严重,预计会出现短缺,促使医学研究所最近对这个问题进行了分析。具有讽刺意味的是,在遗传学和神经科学领域的发现对基础行为科学产生前所未有的影响之际,追求以患者为导向的研究事业的精神病学家却出现了短缺。将这些基础科学见解转化为患者护理领域的发现,对于提高我们对严重精神疾病的理解和治疗至关重要。目前的R25申请旨在通过几个具体目标解决当前精神健康研究教育中的危机,包括1)为医生在临床住院医师培训(PGY I和II)的最早形成阶段提供强化的以患者为导向的研究培训(IMPORT)计划,2)通过在住院医师后期(PGY III和IV)继续进行纵向研究培训来加强这一早期接触,3)促进计划受训者与住院医师后(PGY V)研究培训奖学金机会的联系,以及4)提炼和优化这些经验,以便为全国精神病学住院医师提供以患者为中心的研究培训的国家模式。来自R25的资金,加上耶鲁大学的机构资源,每年将允许多达4名精神科住院医生接受这种专门的纵向研究培训经验。如果成功,该计划将通过增加识别、招聘和留住一支高技能的年轻临床精神病学研究人员队伍,并间接地作为全国其他住院医师培训计划的模板,使国家直接受益。
英文摘要
DESCRIPTION (provided by applicant): Declines in the numbers of physicians pursuing careers in clinical research have raised national concerns about an impending crisis in public health care. While numerous medical fields are affected, the problem in psychiatry is particularly acute, with projected shortages prompting a recent analysis of the problem by the Institute of Medicine. Ironically, shortages of psychiatrists pursing patient-oriented research careers occur at a time when discoveries in the fields of genetics and neuroscience are having an unprecedented impact on the basic behavioral sciences. Translating such basic science insights into discoveries in the patient-care realm will be crucial for improving our understanding and treatment of severe mental illness. The current R25 application is intended to address the current crisis in mental health research education through several specific aims, including 1) to provide a program of Intensive Mentored Patient-Oriented Research Training (IMPORT) for physicians at their earliest, formative stages of clinical residency training (PGY I & II), 2) to build upon this early exposure through continued longitudinal research training in later residency years (PGY III & IV), 3) to facilitate connections of program trainees to post-residency (PGY V) research training fellowship opportunities, and 4) to refine and optimize these experiences so as to provide a national model for training psychiatry residents across the country in patient-oriented research. Funding from the R25, in conjunction with institutional resources at Yale, will allow a total of up to 4 psychiatric residents per year to receive such specialized longitudinal research training experiences. If successful, the program will benefit the country directly, through the increased identification, recruitment and retention of a highly skilled cadre of young clinical psychiatric investigators, and indirectly, as a template for other residency training programs across the country.
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Assessing Glutamate Homeostasis in Cocaine Addiction Using 7T 1H-MRS
  • 批准号:
    9226608
  • 项目类别:
  • 资助金额:
    $25.13万
  • 财政年份:
    2017
  • 负责人:
    ROBERT T MALISON
  • 依托单位:
Imaging Synaptic Density in the Cocaine-Addicted Brain In Vivo using 11C UCB J PET
  • 批准号:
    9335542
  • 项目类别:
  • 资助金额:
    $20.94万
  • 财政年份:
    2017
  • 负责人:
    ROBERT T MALISON
  • 依托单位:
Glutamate-Glutamine Cycling (Vcyc) in Cocaine Abstinence using 13C-MRS
  • 批准号:
    8861373
  • 项目类别:
  • 资助金额:
    $45.92万
  • 财政年份:
    2015
  • 负责人:
    ROBERT T MALISON
  • 依托单位:
Clinical and Educational Core
  • 批准号:
    7797222
  • 项目类别:
  • 资助金额:
    $18.8万
  • 财政年份:
    2010
  • 负责人:
    ROBERT T MALISON
  • 依托单位:
海外基金