NE COBRE: MICROSCOPY CORE RESEARCH FACILITY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 显微镜核心研究设施（MCRF）一直是内布拉斯加州使用最频繁的核心之一，为学术和工业组织的所有研究人员提供最先进的仪器和专业服务。MCRF有两个奥林巴斯共聚焦激光扫描显微镜系统（一个具有直立的范围，另一个具有倒置的系统），能够同时显示双或三荧光标记的材料和两个先进的荧光显微镜与高灵敏度的视频/数码相机。这些成像系统已被使用的大多数NCV成员跨UNL校园和几个成员从UNMC。MCRF经理和工作人员与至少40个故障/PI建立了强有力的研究合作，每年有60-85个教师团体（今年有73个PI）使用。这导致了几个出版物，其中研究小组利用NCV赠款和周的专业知识支持的设备（见出版物列表）。 核心还参与了本科生和研究生教育/培训计划，并在过去一年中为约200名学生组织了成像系统演示。 此外，MCRF一直积极参与资助申请（如NCV，氧化还原中心和细胞信号传导，以及许多个人研究者），并一直是NCV的关键组成部分。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Microscopy Core Research Facility (MCRF) has been one of the most heavily used cores in Nebraska, which provides the-state-of-art instrumentation and professional services to all researchers from both academic and industrial organizations. The MCRF has two Olympus confocal laser scanning microscope systems (one with an upright scope and the other with an inverted system) with the capacity for simultaneous display of double or triple fluorescence labeled materials and two advanced fluorescence microscopes with high-sensitivity video/digital cameras. These imaging systems have been used by most of NCV members cross the UNL campus and by several members from UNMC. The MCRF Manager and staff have set up strong research collaborations with many at least 40 faulty/PIs and has been utilized by 60-85 faculty groups annually (73 PIs in this year). This resulted in several publications in which the research groups utilized the equipment supported by the NCV grant and Zhou's expertise (see list of publications). The Core has also been involved in undergraduate and graduate education/training programs and has organized demonstrations of imaging systems for ~ 200 students during the past year. In addition, the MCRF has been actively participating in grant application (such as NCV, Redox Center, and Cell Signaling, as well as many individual investigators) and has been a key component of the NCV.