Cancer Center Support Grant

描述(由申请人提供)：纪念斯隆-凯特琳癌症中心(MSKCC) 纪念斯隆-凯特琳癌症中心(MSKCC)是一家独立的机构，致力于通过住院和门诊护理、临床和研究培训计划以及广泛的研究活动来控制癌症。MSKCC的研究计划分为三类：基础 研究(细胞行为调控、发育生物学、基因组完整性和分子 结构)；桥梁学科(癌症生物学和实验病理学、实验治疗学、 免疫学和移植、成像和放射科学)和以患者为中心的研究(临床研究和预防、控制和人口研究)。这些计划旨在最大限度地利用庞大的患者群体和广泛的、多学科的临床和实验室研究人员队伍，并鼓励将发现应用于基础科学，以促进多种形式癌症的预防、检测、诊断和治疗。十个研究项目中的科学工作依赖于34个核心设施提供的服务，其中19个将得到癌症中心支持补助金(CCSG)的资助。在接下来的五年里，MSKCC将继续扩大其临床和研究设施以及研究和培训计划；因此，要求增加预算，以在几个调查领域建立新研究人员的实验室，并支持已增长的核心设施，以支持研究企业的需求。

DESCRIPTION (provided by applicant): Memorial Sloan-Kettering Cancer Center (MSKCC) Memorial Sloan Kettering Cancer Center (MSKCC) is a free-standing institution dedicated to the control of cancer through in-patient and out-patient care, clinical and research training programs, and a broad spectrum of research activities. MSKCC's research programs are grouped into three categories: Basic Research (Regulation of Cell Behavior, Developmental Biology, Genomic Integrity, and Molecular Structure); Bridge Disciplines (Cancer Biology and Experimental Pathology, Experimental Therapeutics, Immunology and Transplantation, and Imaging and Radiation Sciences), and Patient-Oriented Research (Clinical Research and Prevention, Control, and Population Research). The programs are designed to optimize the use of a large patient population and an extensive, multi-disciplinary staff of clinical and laboratory-based investigators and to encourage the application of discoveries in the basic sciences in a way that advances the prevention, detection, diagnosis, and treatment of many forms of cancer. Scientific work in the ten research programs depends on services provided by 34 core facilities, 19 of which will receive funding from the Cancer Center Support Grant (CCSG). During the next five years, MSKCC will continue to enlarge its clinical and research facilities and its research and training programs; therefore, an expanded budget is requested to establish the laboratories of new investigators in several fields of inquiry and to support the core facilities which have grown to support the needs of the research enterprise.