Community Development of the Cell Centered Database

描述（由申请人提供）：细胞中心数据库（CCDB）于2002年发布，是一个可通过网络访问的数据库，用于获取来自光学和电子显微镜成像（包括相关光学和电子显微镜）的高分辨率2D、3D和4D数据。CCDB包含并托管了介于总体形态和大分子结构之间的尺寸范围内的许多类型的数据-所谓的“中尺度”。这些数据以及承载和服务这些数据的软件基础设施在范围上是独特的，向社区提供了充满技术上难以获得但内容非常丰富的信息的数据集，使它们对于开发细胞和组织中发生的结构和生理过程的计算模型特别有价值。从1998年项目开始，CCDB就被设想为一个基于网格和/或Web的联邦数据库系统，它开创了一个分布式、可连接的存储库系统，用于管理和共享不断增长的显微镜研究社区的数据。该提案旨在为细胞中心数据库日益扩大的用户群体提供一个稳定的支持基础，方法是改进核心服务，建立必要的设施，使细胞中心数据库的数据和软件能够由不断扩大的参与者群体公开分享、修改、扩展、编辑和记录。拟议的工作分为三个具体目标：目标1。开源CCDB：目前的系统基础设施将从一个具有明确社区要求的中央支持的研究产品转化为一个为社区范围的贡献、定制和改进而量身定制的行业模型开放源码项目。目标二：国开行核心服务：CCDB的主要组件（模式、核心服务）将通过开源分发模型打包，以供社区分发和改进。文档将沿着规范，用于扩展“社区贡献”，以存储/收集核心CCDB服务。目标3：CCDB客户端工具：将对现有的CCDB客户端工具进行打包和分发，供最终用户群体使用。

DESCRIPTION (provided by applicant): The Cell Centered Database (CCDB) was released in 2002 as a web-accessible database for high resolution 2D, 3D and 4D data derived from light and electron microscopic imaging, including correlated light and electron microscopy. The CCDB encompasses and hosts many types of data in the dimensional range lying between gross morphology and macromolecular structure - the so-called "mesoscale". These data and the software infrastructure that hosts and serves them are unique in scope, presenting to the community data sets laden with information which is technically difficult to obtain but very rich in content, making them particularly valuable for developing computational models of structures and physiological processes that occur in cells and tissues. Envisioned as a grid and/or web-based federated database system from the beginning of the project in 1998, the CCDB pioneered the production of a distributed, connectable repository system for managing and sharing data for a growing research community of microscopists. This proposal aims to provide a stable base of support for a growing community of users of the Cell Centered Database, by refining core services and establishing the facilities needed for CCDB data and software to be openly shared, modified, extended, edited and documented by the expanding participant group. The proposed work is organized into three specific aims: Aim 1. Open Source CCDB: The current system infrastructure will be translated from a centrally supported research product with defined community requirements to an industrymodeled open source project tailored for community wide contribution, customization and refinement. Aim 2: CDB Core Services: The principal components (schema, core services) of the CCDB will be packaged for community distribution and refinement via open source distribution model. Documentaiton will be provided along with specifications for expanded "community contribution" to a repository/collection of core CCDB services. Aim 3: CCDB Client Tools: Existing CCDB client tools will be packaged and distributed for use by the end-user community.