Community Development of the Cell Centered Database

描述（由申请人提供）：细胞中心数据库（CCDB）于2002年发布，是一个可访问的高分辨率2D， 3D和4D数据数据库，来自于光和电子显微镜成像，包括相关光和电子显微镜。CCDB包含并托管了介于大体形态和大分子结构（即所谓的“中尺度”）之间的许多类型的数据。这些数据和承载和服务它们的软件基础设施在范围上是独一无二的，向社区数据集呈现了充满信息的数据集，这些信息在技术上很难获得，但内容非常丰富，这使得它们对于开发细胞和组织中发生的结构和生理过程的计算模型特别有价值。从1998年项目开始，CCDB就被设想为一个网格和/或基于web的联合数据库系统，CCDB率先生产了一个分布式的、可连接的存储库系统，用于管理和共享日益增长的显微镜研究社区的数据。该提案旨在通过完善核心服务和建立CCDB数据和软件所需的设施，为不断扩大的参与者群体公开共享、修改、扩展、编辑和记录，为不断增长的Cell中心数据库用户社区提供稳定的支持基础。拟议的工作分为三个具体目标：目标1。开源CCDB：当前的系统基础设施将从具有明确社区需求的集中支持的研究产品转变为为社区广泛贡献、定制和改进而量身定制的行业模型开源项目。目标2:CDB核心服务：CCDB的主要组件（模式、核心服务）将被打包，以便通过开源分发模型进行社区分发和细化。文档将与扩展到核心CCDB服务的存储库/集合的“社区贡献”规范一起提供。目标3:CCDB客户端工具：现有的CCDB客户端工具将被打包和分发，以供最终用户社区使用。

DESCRIPTION (provided by applicant): The Cell Centered Database (CCDB) was released in 2002 as a web-accessible database for high resolution 2D, 3D and 4D data derived from light and electron microscopic imaging, including correlated light and electron microscopy. The CCDB encompasses and hosts many types of data in the dimensional range lying between gross morphology and macromolecular structure - the so-called "mesoscale". These data and the software infrastructure that hosts and serves them are unique in scope, presenting to the community data sets laden with information which is technically difficult to obtain but very rich in content, making them particularly valuable for developing computational models of structures and physiological processes that occur in cells and tissues. Envisioned as a grid and/or web-based federated database system from the beginning of the project in 1998, the CCDB pioneered the production of a distributed, connectable repository system for managing and sharing data for a growing research community of microscopists. This proposal aims to provide a stable base of support for a growing community of users of the Cell Centered Database, by refining core services and establishing the facilities needed for CCDB data and software to be openly shared, modified, extended, edited and documented by the expanding participant group. The proposed work is organized into three specific aims: Aim 1. Open Source CCDB: The current system infrastructure will be translated from a centrally supported research product with defined community requirements to an industrymodeled open source project tailored for community wide contribution, customization and refinement. Aim 2: CDB Core Services: The principal components (schema, core services) of the CCDB will be packaged for community distribution and refinement via open source distribution model. Documentaiton will be provided along with specifications for expanded "community contribution" to a repository/collection of core CCDB services. Aim 3: CCDB Client Tools: Existing CCDB client tools will be packaged and distributed for use by the end-user community.