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Molecular dissection of the function of caveolae

Molecular dissection of the function of caveolae
小凹功能的分子解剖
批准号:
nhmrc : GNT1140064
负责人:
Prof Robert Parton
金额:
$115.63万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --

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中文摘要
翻译
细胞是生命的基石。这一建议集中在细胞表面、质膜和称为小凹的特殊结构上,这是动物细胞的一个丰富特征。凹陷改变是许多人类疾病的特征。在这项提案中,我们将讨论小窝的功能。我们将测试这样一种观点,即当细胞受到压力时,蛋白质从小窝释放到细胞内,形成一种在疾病中被破坏的新的信号通路。
英文摘要
The cell is the building block of life. This proposal focusses on the surface of the cell, the plasma membrane, and specialised structures called caveolae that are an abundant feature of animal cells. Altered caveolae are a feature of many human disease conditions. In this proposal we will address the function of caveolae. We will test the idea that proteins are released from caveolae into the cell when cells are stressed forming a novel signalling pathway disrupted in disease.
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Tracking nanoparticles: from cell culture to in vivo delivery
  • 批准号:
    FL210100107
  • 项目类别:
    Australian Laureate Fellowships
  • 资助金额:
    $207.08万
  • 财政年份:
    2022
  • 负责人:
    Prof Robert Parton
  • 依托单位:
Structural and Functional Analysis of Plasma Membrane Microdomains in Health and Disease
  • 批准号:
    nhmrc : GNT1156489
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $88.83万
  • 财政年份:
    2019
  • 负责人:
    Prof Robert Parton
  • 依托单位:
Molecular dissection of the function of caveolae
  • 批准号:
    nhmrc : 1140064
  • 项目类别:
    Project Grants
  • 资助金额:
    $78.18万
  • 财政年份:
    2018
  • 负责人:
    Prof Robert Parton
  • 依托单位:
The plasma membrane in health and disease
  • 批准号:
    nhmrc : GNT1058565
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $82.29万
  • 财政年份:
    2014
  • 负责人:
    Prof Robert Parton
  • 依托单位:
海外基金