High Resolution EM Tomography of Specialised Plasma Membrane Domains

专业质膜域的高分辨率 EM 断层扫描

• 批准号: DP0662761
• 负责人: Prof Robert Parton
• 金额: $ 19.38万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0662761
• 关键词: Resolution; EM; Tomography; Specialised; Plasma

This project will provide National benefits in two major areas. Firstly, these studies will greatly increase our understanding of the cellular structures which are crucial to the functioning of cells in the body. Understanding the structure of the components of animal cells in three dimensions will provide long-term benefits in the quest to understand how a cell works in health and what goes wrong in disease. Secondly, this project will allow us to develop the new method of electron microscope tomography and apply it to a crucial question in biology. This will be a vital technique for Australian investigators in the coming years and this project will allow scientists and students to be trained in these state-of-the-art techniques.

该项目将在两个主要领域为国家带来好处。首先，这些研究将大大增加我们对细胞结构的理解，这些结构对体内细胞的功能至关重要。了解动物细胞组成部分的三维结构将为了解细胞在健康状态下如何工作以及疾病中出现什么问题提供长期利益。其次，这个项目将使我们能够开发电子显微镜断层扫描的新方法，并将其应用于生物学中的一个关键问题。这将是澳大利亚调查人员在未来几年中的一项重要技术，该项目将使科学家和学生能够接受这些最先进技术的培训。