Molecular dissection of proteins that regulate the invasion of Toxoplasma gondii into human cells
Molecular dissection of proteins that regulate the invasion of Toxoplasma gondii into human cells
批准号:
nhmrc : 575523
负责人:
A/Pr Christopher Tonkin
金额:
$25.84万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31
中文摘要
刚地弓形虫是一种专性细胞内寄生虫负责先天性出生缺陷和免疫受损个体的疾病。我建议鉴定和表征弓形虫入侵人体细胞所必需的分子。这代表了这种重要生物体引起的疾病的治疗干预的新靶点。
英文摘要
Toxoplasma gondii is an obligate intracellular parasite responsible for congenital birth defects and disease of immuno-compromised individuals. I propose to identify and characterize molecules essential for T. gondii invasion into human cells. These represent novel targets for therapeutic intervention for disease caused by this important organism.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Targeting acute and chronic toxoplasmosis
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批准号:nhmrc : GNT1123218
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项目类别:Project Grants
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资助金额:$53.11万
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财政年份:2017
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负责人:A/Pr Christopher Tonkin
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依托单位:
Targeting acute and chronic toxoplasmosis
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批准号:nhmrc : 1123218
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项目类别:Project Grants
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资助金额:$36.24万
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财政年份:2017
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负责人:A/Pr Christopher Tonkin
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依托单位:
Regulation of toxoplasma by the NLRP1 inflammasome
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批准号:nhmrc : 1057815
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项目类别:Project Grants
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资助金额:$41.55万
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财政年份:2014
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负责人:A/Pr Christopher Tonkin
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依托单位:
Functional analysis of the Toxoplasma Myosin driving tissue dissemination and host cell invasion
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批准号:nhmrc : 1047806
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项目类别:Project Grants
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资助金额:$50.89万
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财政年份:2013
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负责人:A/Pr Christopher Tonkin
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依托单位:
Functional Dissection of Invasion Motor Regulation in Toxoplasma gondii
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批准号:nhmrc : 1025598
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项目类别:Project Grants
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资助金额:$33.37万
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财政年份:2012
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负责人:A/Pr Christopher Tonkin
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依托单位:
Sequence requirements for targeting parasite proteins to the red blood cell membrane in the malaria parasite P. falcipar
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批准号:nhmrc : 575513
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项目类别:Early Career Fellowships
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资助金额:$0.48万
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财政年份:2009
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负责人:A/Pr Christopher Tonkin
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依托单位:
Regulation of actin polymerization during malaria parasite invasion of the human erythrocyte
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批准号:nhmrc : 516747
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项目类别:NHMRC Project Grants
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资助金额:$21.21万
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财政年份:2008
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负责人:A/Pr Christopher Tonkin
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依托单位:
Sequence requirements for targeting parasite proteins to the red blood cell membrane in the malaria parasite P. falcipar
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批准号:nhmrc : 356264
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项目类别:Early Career Fellowships
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资助金额:$18.1万
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财政年份:2005
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负责人:A/Pr Christopher Tonkin
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依托单位:
海外基金