Renovations at Johns Hopkins University to Support Expanded Macaque Production

描述(由申请人提供)：这项提案要求提供500,000美元，以部分资助约翰霍普金斯研究农场12号楼的翻新和翻新，以适应P40赠款支持的SPF猪尾猕猴群体的增长(Robert J.Adams，Pi，P40 RR019995-01A2，Development of a SPF Macaca nomestrina Proking Colony)。约翰·霍普金斯大学的动物护理和利用项目规模大，内容丰富，涉及多种实验动物。长期以来，非人类灵长类动物的使用一直是该项目的一个突出特点，霍普金斯研究农场校园里的恒河猴繁殖群体(Macaca Mulatta)已经维持了几十年，以确保我们的研究项目有充足的SPF恒河猴供应。从2003年开始，我们着手开发一个用于小尾猴(Macaca Nomestrina)的SPF繁殖群体，利用机构资源来满足JHU研究计划对这种动物模型日益增长的需求，并缓解我们在为外部群体获得这种物种时遇到的困难。12号楼已经10多年没有使用了，而且已经有些破旧，但经过外部建筑师和工程师的广泛审查，已经确定该建筑可以相对容易地进行翻新和翻新。12号楼毗邻13号楼，也就是殖民地现在居住的地方。作为这项提案的一部分，这两座建筑将共用一台应急发电机和一口水井。

DESCRIPTION (provided by applicant): This proposal requests $500,000 to partially fund the renovation and refurbishment of Building 12 at the Johns Hopkins Research Farm to accommodate the growth of a P40 grant supported SPF Pigtail macaque colony (Robert J. Adams, PI, P40 RR019995-01A2, Development of an SPF Macaca nemestrina Breeding Colony). The animal care and use program of Johns Hopkins University is large and highly diversified involving a broad spectrum of laboratory animal species. Non-human primate use has long been a prominent feature of the program, and a rhesus monkey breeding colony (Macaca mulatta) has been maintained on the Hopkins Research Farm campus for decades to ensure that an ample supply of SPF rhesus macaques was available for our research programs. Beginning in 2003, we embarked upon the development of an SPF breeding colony for pigtail macaques (Macaca nemestrina) using institutional resources to meet the growing needs for this animal model in JHU research programs and to alleviate the difficulties we had encountered in obtaining this species for outside colonies. Building 12 has not been used for over 10 years, and has undergone some deterioration, but after extensive review by outside Architects and Engineers, it has been determined that the building can be renovated and refurbished relatively easily. Building 12 is adjacent to Building 13 in which the colony now resides. The two buildings will share an emergency electrical generator and water well requested as part of this proposal.